Successfully Treated Abdominal Pregnancy Causing Hemoperitoneum Using Combined Surgical and Systemic Methotrexate Therapy: A Case Report and Review of Cases Treated at Kyushu University Hospital

التفاصيل البيبلوغرافية
العنوان: Successfully Treated Abdominal Pregnancy Causing Hemoperitoneum Using Combined Surgical and Systemic Methotrexate Therapy: A Case Report and Review of Cases Treated at Kyushu University Hospital
المؤلفون: Soko Uchida, Hiroaki Kobayashi, Nobuko Yasutake, Kiyoko Kato, Hiroko Oishi, Ryosuke Tsunematsu, Hideaki Yahata
المصدر: Gynecologic and Obstetric Investigation. 76:188-192
بيانات النشر: S. Karger AG, 2013.
سنة النشر: 2013
مصطلحات موضوعية: Adult, medicine.medical_specialty, Gestational sac, Chorionic Gonadotropin, Pregnancy, Pregnancy, Abdominal, medicine, Humans, Positive Pregnancy Test, Hemoperitoneum, Abortifacient Agents, Nonsteroidal, Laparotomy, Ectopic pregnancy, business.industry, Obstetrics and Gynecology, medicine.disease, Surgery, Methotrexate, medicine.anatomical_structure, Reproductive Medicine, Abdominal pregnancy, Abdomen, Female, medicine.symptom, business, Abdominal surgery
الوصف: Abdominal pregnancy is a rare condition that accounts for only 1% of all ectopic pregnancies but results in high maternal morbidity and mortality. We present a case of abdominal pregnancy with massive peritoneal bleeding successfully treated using systemic methotrexate (MTX). A 34-year-old woman with amenorrhea for 8 weeks and a positive pregnancy test was referred for evaluation of ectopic pregnancy. Transvaginal ultrasonographic scan showed a gestational sac measuring 25 mm in diameter containing a viable embryo in the cul-de-sac and a considerable amount of free fluid in the patient's lower abdomen and pelvis. Laboratory parameters showed that her hemoglobin concentration was 5.8 g/dl and serum human chorionic gonadotropin concentration was 13,195 mIU/ml. Emergency surgery revealed an abdominal pregnancy in the cul-de-sac and a massive intra-abdominal hemorrhage. After a hemostasis procedure, the patient was successfully treated using systemic MTX. We also present the review of abdominal pregnancy cases treated using systemic MTX at our institution over 10 years. Systemic MTX treatment for abdominal pregnancy is safe and effective and makes it possible to avoid the risk of excessive bleeding by surgical resection of the implantation site.
تدمد: 1423-002X
0378-7346
DOI: 10.1159/000353980
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563ff41159616ca5af72cb021b2c5657
https://doi.org/10.1159/000353980
Rights: CLOSED
رقم الانضمام: edsair.doi.dedup.....563ff41159616ca5af72cb021b2c5657
قاعدة البيانات: OpenAIRE
الوصف
تدمد:1423002X
03787346
DOI:10.1159/000353980