Parental Whole Life Cycle Exposure to Dietary Methylmercury in Zebrafish (Danio rerio) Affects the Behavior of Offspring
| العنوان: | Parental Whole Life Cycle Exposure to Dietary Methylmercury in Zebrafish (Danio rerio) Affects the Behavior of Offspring |
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| المؤلفون: | Jessica A. Head, Rebekah H. Klingler, Francisco X. Mora-Zamorano, Cheryl A. Murphy, Michael J. Carvan, Niladri Basu |
| المصدر: | Environmental Science & Technology. 50:4808-4816 |
| بيانات النشر: | American Chemical Society (ACS), 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | 0301 basic medicine, Offspring, Foraging, Danio, Zoology, 010501 environmental sciences, 01 natural sciences, Locomotor activity, Predation, Toxicology, 03 medical and health sciences, chemistry.chemical_compound, Animals, Environmental Chemistry, Methylmercury, Zebrafish, Swimming, 0105 earth and related environmental sciences, Behavior, Animal, biology, General Chemistry, Methylmercury Compounds, biology.organism_classification, Diet, 030104 developmental biology, Behavioral test, chemistry |
| الوصف: | Methylmercury (MeHg) is an established neurotoxicant of concern to fish-eating organisms. While most studies have focused on the fish consumers, much less is known about the effects of MeHg on the fish themselves, especially following exposures to chronic and environmentally relevant scenarios. Here we evaluated the behavioral effects of developmental MeHg insult by exposing parental generations of zebrafish to an environmentally realistic MeHg dietary concentration (1 ppm) and two higher concentrations (3 and 10 ppm) throughout their whole life span. Upon reaching adulthood, their offspring were analyzed through a series of behavioral tests, including the visual-motor response (VMR) assay, analysis of spontaneous swimming and evaluation of foraging efficiency. The VMR assay identified decreased locomotor output in the 6 day postfertilization (dpf) offspring of fish exposed to 3 and 10 ppm MeHg. However, in a second test 7 dpf fish revealed an increase in locomotor activity in all MeHg exposures tested. Increases in locomotion continued to be observed until 16 dpf, which coincided with increased foraging efficiency. These results suggest an association between MeHg and hyperactivity, and imply that fish chronically exposed to MeHg in the wild may be vulnerable to predation. |
| تدمد: | 1520-5851 0013-936X |
| DOI: | 10.1021/acs.est.6b00223 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524c90aa2c87cd7ed9626330f432093a https://doi.org/10.1021/acs.est.6b00223 |
| رقم الانضمام: | edsair.doi.dedup.....524c90aa2c87cd7ed9626330f432093a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15205851 0013936X |
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| DOI: | 10.1021/acs.est.6b00223 |