Chemical and Biophysical Signatures of the Protein Corona in Nanomedicine
| العنوان: | Chemical and Biophysical Signatures of the Protein Corona in Nanomedicine |
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| المؤلفون: | Jiayu Ren, Nicholas Andrikopoulos, Kelly Velonia, Huayuan Tang, Rong Cai, Feng Ding, Pu Chun Ke, Chunying Chen |
| المصدر: | Journal of the American Chemical Society. 144:9184-9205 |
| بيانات النشر: | American Chemical Society (ACS), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Nanomedicine, Colloid and Surface Chemistry, Humans, Nanoparticles, Proteins, Protein Corona, General Chemistry, Biochemistry, Catalysis |
| الوصف: | An inconvenient hurdle in the practice of nanomedicine is the protein corona, a spontaneous collection of biomolecular species by nanoparticles in living systems. The protein corona is dynamic in composition and may entail improved water suspendability and compromised delivery and targeting to the nanoparticles. How much of this nonspecific protein ensemble is determined by the chemistry of the nanoparticle core and its surface functionalization, and how much of this entity is dictated by the biological environments that vary spatiotemporally |
| تدمد: | 1520-5126 0002-7863 |
| DOI: | 10.1021/jacs.2c02277 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a767673b4555e8fb7bcfd284d8b88c https://doi.org/10.1021/jacs.2c02277 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....51a767673b4555e8fb7bcfd284d8b88c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15205126 00027863 |
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| DOI: | 10.1021/jacs.2c02277 |