Long-term characteristics of exudative age-related macular degeneration in Japanese patients
| العنوان: | Long-term characteristics of exudative age-related macular degeneration in Japanese patients |
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| المؤلفون: | Masaaki Saito, Tomohiro Iida, Kuniharu Saito, Mariko Kano, Kanako Itagaki, Ichiro Maruko, Tetsuju Sekiryu |
| المصدر: | PLoS ONE PLoS ONE, Vol 16, Iss 12, p e0261320 (2021) |
| بيانات النشر: | Public Library of Science, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, Eye Diseases, Vision, Visual Acuity, Social Sciences, Drug research and development, Cardiovascular Medicine, Chi Square Tests, Diagnostic Radiology, Macular Degeneration, Medical Conditions, Clinical trials, Mathematical and Statistical Techniques, Japan, Medicine and Health Sciences, Psychology, Geriatric Ophthalmology, Cardiovascular Imaging, Fluorescein Angiography, Aged, 80 and over, Multidisciplinary, Phase I clinical investigation, Radiology and Imaging, Retinal Degeneration, Statistics, Angiography, Middle Aged, Physical Sciences, Medicine, Retinal Disorders, Sensory Perception, Female, Anatomy, Tomography, Optical Coherence, Research Article, Phase V clinical investigation, Imaging Techniques, Science, Cardiology, Signs and Symptoms, Ocular System, Diagnostic Medicine, Humans, Statistical Methods, Statistical Hypothesis Testing, Aged, Retrospective Studies, Pharmacology, Cognitive Psychology, Biology and Life Sciences, eye diseases, Choroidal Neovascularization, Research and analysis methods, Ophthalmology, Geriatrics, Macular Disorders, Clinical medicine, Lesions, Eyes, Cognitive Science, Perception, Head, Mathematics, Neuroscience |
| الوصف: | Purpose The present study aimed to evaluate the clinical characteristics of exudative age-related macular degeneration (AMD) in Japanese patients over a 10-year period and to compare the past our report. Methods We retrospectively reviewed 1,600 treatment-naïve patients (1,777 eyes) with exudative AMD. The 10 years were divided into 2-year phases I to V. Results Of the 1,600 patients, 720 (45.0%), 733 (45.8%), 98 (6.1%), and 49 (3.1%) were diagnosed with typical AMD, polypoidal choroidal vasculopathy (PCV), retinal angiomatous proliferation, and combined subtypes, respectively. The prevalence of PCV decreased from 54.7% in phase I to 46.0% at phase V. Of the 1,777 eyes, the mean baseline logarithm of the minimum angle of resolution best-corrected visual acuities (BCVAs) in phases I, II, III, IV, and V were 0.70, 0.66, 0.55, 0.50, and 0.48, respectively. Phases III, IV, and V had significantly (P = 0.0012, P Conclusions Although the prevalence of PCV decreased from 54.7% in phase I to 46.0% at phase V, PCV has nevertheless been highly prevalent in Japanese patients with AMD compared with Caucasian patients. The annual better baseline VAs and smaller lesion sizes over time might be related to development of treatment and better concerns about AMD. |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519481633369e27351fcc0284a34e811 http://europepmc.org/articles/PMC8670714 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....519481633369e27351fcc0284a34e811 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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