Influence of menthol and green apple e-liquids containing different nicotine concentrations among youth e-cigarette users
| العنوان: | Influence of menthol and green apple e-liquids containing different nicotine concentrations among youth e-cigarette users |
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| المؤلفون: | Barry G. Green, Eugenia Buta, Ralitza Gueorguieva, Asti Jackson, Dana A. Cavallo, Hanno C. Erythropel, Stephanie S. O'Malley, Tore Eid, Suchitra Krishnan-Sarin, Grace Kong |
| المصدر: | Exp Clin Psychopharmacol |
| بيانات النشر: | American Psychological Association (APA), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, Nicotine, Taste, Adolescent, Subjective effects, Electronic Nicotine Delivery Systems, Article, Random order, chemistry.chemical_compound, Nicotine concentration, Humans, Medicine, Pharmacology (medical), Food science, Flavor, Pharmacology, business.industry, food and beverages, Tobacco Products, Sweetness, equipment and supplies, Flavoring Agents, Menthol, Psychiatry and Mental health, chemistry, Malus, Female, business, medicine.drug |
| الوصف: | E-cigarettes are popular among adolescents. Given that flavors enhance e-cigarette appeal, this study examined the influence of flavors on nicotine in e-cigarettes. Youth e-cigarette users (average 26.2 days [SD = 3.6] in past 28 days) were randomized to use e-cigarettes containing 6 or 12 mg/mL of freebase nicotine and completed 4 test sessions. During the first 3 test sessions, participants completed 3 fixed puffing bouts (1 puffing bout = 10 puffs, 3 s each, 30-s interval), using menthol, green-apple, and unflavored e-liquids (50 propylene glycol [PG]/50 vegetable glycerin [VG]) with their assigned nicotine concentration in a random order using a ∼5.5-W V2 e-cigarette device. After each puffing bout, participants assessed subjective effects of nicotine and flavor. In the 4th test session, participants used any of the e-liquids they had tried in the earlier sessions, ad libitum for 60 min and the amount of e-liquid used for each flavor and the number of puffs was assessed. Participants (n = 49; 6 mg/mL [n = 24]; 12 mg/mL [n = 25]) were 63.3% male, 65.3% non-Hispanic White with an average age of 18.7 (SD = 0.9). Mixed models analysis revealed that green apple and 6 mg/mL of nicotine independently increased liking of e-cigarette taste. In addition, green apple produced higher ratings of fruitiness, sourness, sweetness, and menthol produced higher ratings of coolness. We did not observe any interactions between nicotine and flavor. Youth liked the taste of e-liquids containing green-apple flavor or low nicotine concentration which highlights the appeal of fruit flavors in e-cigarettes to adolescents. (PsycInfo Database Record (c) 2021 APA, all rights reserved). |
| تدمد: | 1936-2293 1064-1297 |
| DOI: | 10.1037/pha0000368 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a540cccf7e04f07b70b1ae57e24701 https://doi.org/10.1037/pha0000368 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....50a540cccf7e04f07b70b1ae57e24701 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19362293 10641297 |
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| DOI: | 10.1037/pha0000368 |