Multiparametric Magnetic Resonance Imaging in the Assessment of Pulmonary Hypertension: Initial Experience of a One-Stop Study
| العنوان: | Multiparametric Magnetic Resonance Imaging in the Assessment of Pulmonary Hypertension: Initial Experience of a One-Stop Study |
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| المؤلفون: | Edson Marchiori, Gisela Meyer, Matheus Zanon, Gabriel Sartori Pacini, Fernanda B. Spilimbergo, Guilherme Watte, Stephan Atmayer, Bruno Hochhegger |
| المصدر: | Repositório Institucional PUCRS Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) instacron:PUC_RS |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Pulmonary and Respiratory Medicine, Adult, Male, medicine.medical_specialty, Cardiac Catheterization, Pulmonary Circulation, Heart disease, Hypertension, Pulmonary, Perfusion Imaging, Magnetic Resonance Imaging, Cine, 030204 cardiovascular system & hematology, Scintigraphy, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Risk Factors, Multidetector Computed Tomography, medicine, Humans, Multiparametric Magnetic Resonance Imaging, Retrospective Studies, medicine.diagnostic_test, business.industry, Interstitial lung disease, Hemodynamics, Reproducibility of Results, Magnetic resonance imaging, Gold standard (test), Middle Aged, medicine.disease, Pulmonary hypertension, medicine.anatomical_structure, Vascular resistance, Female, Radiology, business, Lung Diseases, Interstitial, Pulmonary Embolism, Preliminary Data |
| الوصف: | Our goal was to assess the diagnostic performance of magnetic resonance imaging (MRI) as a single method to diagnose pulmonary hypertension (PH) compared to right heart catheterization (RHC), computed tomography (CT), and ventilation/perfusion (V/Q) scintigraphy. We identified 35 patients diagnosed with PH by RHC in our institution who have also undergone a CT, a scintigraphy, and an MRI within a month. All cases were discussed in multidisciplinary meetings. We performed correlations between the MRI-derived hemodynamic parameters and those from RHC. The sensitivity and specificity of MRI were determined to identify its diagnostic performance to identify chronic thromboembolic pulmonary hypertension (CTEPH) and interstitial lung disease PH. The gold standard reference for the diagnosis of CTEPH and ILD was based on a review of multimodality imaging (V/Q scintigraphy and CT scan) and clinical findings. Our results showed a good correlation between the hemodynamic parameters of cardiac MRI and RHC. Pulmonary vascular resistance had the best correlation between both methods (r = 0.923). The sensitivity and specificity of MRI to diagnose CTEPH was 100 and 96.8%, respectively. For the ILD-related PH, the MRI yielded a sensitivity of 60.0% and a specificity of 100%. Additionally, cardiac MRI was able to confirm all cases of PAH due to congenital heart disease initially detected by echocardiography. MRI represents a promising imaging modality as an initial, single-shot study, for patients with suspected PH with the advantages of being non-invasive and having no radiation exposure. |
| تدمد: | 1432-1750 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f03060134d23228f6b7dfb631c9f850 https://pubmed.ncbi.nlm.nih.gov/29876648 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....4f03060134d23228f6b7dfb631c9f850 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14321750 |
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