The relationship between severity of disease and vitamin D levels in children with atopic dermatitis
| العنوان: | The relationship between severity of disease and vitamin D levels in children with atopic dermatitis |
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| المؤلفون: | Didem Dizman, Dilek Biyik Ozkaya, Aysegul Dogan Demir, Nahide Onsun, Ozlem Su, Selcuk Uzuner, Anil Gulsel Bahali |
| المساهمون: | ONSUN, Nahide |
| المصدر: | Advances in Dermatology and Allergology, Vol 34, Iss 3, Pp 224-227 (2017) Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii |
| بيانات النشر: | Termedia Publishing House, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Vitamin, medicine.medical_specialty, Allergy, lcsh:Internal medicine, vitamin D, Dermatology, Disease, Gastroenterology, 030207 dermatology & venereal diseases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Vitamin D and neurology, lcsh:Dermatology, Immunology and Allergy, SCORAD, Su O., BEHALI A. G. , DEMIR A. D. , OZKAYA D. B. , Uzuner S., Dizman D., Onsun N., -The relationship between severity of disease and vitamin D levels in children with atopic dermatitis-, POSTEPY DERMATOLOGII I ALERGOLOGII, cilt.34, ss.224-227, 2017, Prospective cohort study, lcsh:RC31-1245, Original Paper, SCORing Atopic Dermatitis, medicine.diagnostic_test, atopic dermatitis, business.industry, Atopic dermatitis, lcsh:RL1-803, medicine.disease, Serum vitamin D level, 030228 respiratory system, chemistry, business |
| الوصف: | Introduction : Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disorder. Vitamin D is a liposoluble vitamin synthesized mainly in the skin. Vitamin D has several effects on the skin. Aim : To assess the serum level of vitamin D in children with AD and determine its relation to AD severity. Material and methods : Sixty patients with AD were enrolled in the study. We evaluated disease severity using the SCORing Atopic Dermatitis (SCORAD) index. The control group consisted of 37 healthy subjects. Results : The mean serum concentration of 25(OH)D3 in patients with AD was not statistically different from control subjects (p = 0.065). The vitamin D level was significantly lower in moderate and severe AD compared with mild AD, and this difference was statistically significant (p = 0.001 and p = 0.004). Vitamin D showed a negative correlation with serum total IgE levels (p = 0.007). There was no significant correlation between total IgE levels and SCORAD scores (p = 0.089). Conclusions : This study suggests that a low serum vitamin D level is inversely associated with severity of AD in children. Vitamin D has not been included in the routine treatment of AD because of the conflicting results of various studies. Thus, there is a need for more detailed and prospective studies. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2299-0046 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d64f15dbeb25231edd7624168fad38b https://www.termedia.pl/The-relationship-between-severity-of-disease-and-vitamin-D-levels-in-children-with-atopic-dermatitis,7,29509,1,1.html |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....4d64f15dbeb25231edd7624168fad38b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22990046 |
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