The Unexpected Helical Supramolecular Assembly of a Simple Achiral Acetamide Tecton Generates Selective Water Channels
| العنوان: | The Unexpected Helical Supramolecular Assembly of a Simple Achiral Acetamide Tecton Generates Selective Water Channels |
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| المؤلفون: | Dan G. Dumitrescu, Jordi Rull‐Barull, Anthony R. Martin, Nathalie Masquelez, Maurizio Polentarutti, Annie Heroux, Nicola Demitri, Giorgio Bais, Ionut‐Tudor Moraru, Romuald Poteau, Muriel Amblard, Andraž Krajnc, Gregor Mali, Yves‐Marie Legrand, Arie van der Lee, Baptiste Legrand |
| المساهمون: | Elettra Sincrotrone Trieste, Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), Université de Montpellier (UM), Institut Européen des membranes (IEM), Babes-Bolyai University [Cluj-Napoca] (UBB), Laboratoire de physique et chimie des nano-objets (LPCNO), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Fédération de recherche « Matière et interactions » (FeRMI), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), National Institute of Chemistry, Bio-inspired Chemistry and Ecological Innovations (ChimEco), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM) |
| المصدر: | Chemistry-A European Journal Chemistry-A European Journal, 2022, 28 (33), pp.e202200383. ⟨10.1002/chem.202200383⟩ |
| بيانات النشر: | HAL CCSD, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | [CHIM.ORGA]Chemical Sciences/Organic chemistry, Acetamides, Organic Chemistry, Water, Hydrogen Bonding, General Chemistry, Aquaporins, Crystallization, Catalysis |
| الوصف: | International audience; Achiral 2-hydroxy-N-(diphenylmethyl)acetamide (HNDPA) crystallizes in the P61 chiral space group as a hydrate, building up permeable chiral crystalline helical water channels. The crystallization driven chiral self-resolution process is highly robust, with the same air stable crystalline form readily obtained from a variety of conditions. Interestingly, the HNDPA supramolecular helix inner pore is filled by a helical water wire. The whole edifice is mainly stabilized by robust hydrogen bonds involving the HNDPA amide bonds and CH…π interactions between the HNDPA phenyl groups. The crystalline structure shows a breathing behavior, with completely reversible release and reuptake of water inside the chiral channel, under ambient conditions. Importantly, the HNDPA channel is able to transport water very efficiently and selectively in biomimetic conditions. With a permeability per channel of 3.3 million water molecules per second in large unilamellar vesicles (LUV) and a total selectivity against NaCl, the HNDPA channel is a very promising functional nanomaterial for future applications. |
| اللغة: | English |
| تدمد: | 0947-6539 1521-3765 |
| DOI: | 10.1002/chem.202200383⟩ |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3a30e64ed24ead07fe1d3828042e79 https://hal.science/hal-03643372v2/document |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....4a3a30e64ed24ead07fe1d3828042e79 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 09476539 15213765 |
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| DOI: | 10.1002/chem.202200383⟩ |