التفاصيل البيبلوغرافية
| العنوان: |
Salivary protein changes in response to acute stress in medical residents performing advanced clinical simulations: a pilot proteomics study |
| المؤلفون: |
Simiao Ye, Kenneth Hensley, Paul Rega, Donald B. White, Rachel K. Marvin, Muncharie B. Saepoo, David R. Giovannucci, Viviane Kazan, Rong Liu, Dragan Isailovic |
| بيانات النشر: |
Taylor & Francis, 2017. |
| سنة النشر: |
2017 |
| مصطلحات موضوعية: |
Adult, Male, Proteomics, 0301 basic medicine, Emergency Medical Services, Pathology, medicine.medical_specialty, Saliva, Health, Toxicology and Mutagenesis, Clinical Biochemistry, Physiology, Pilot Projects, Biochemistry, Article, Mass Spectrometry, Young Adult, 03 medical and health sciences, medicine, Humans, Amylase, Salivary Proteins and Peptides, Acute stress, Morning, Gel electrophoresis, biology, business.industry, Internship and Residency, Protein markers, 030104 developmental biology, biology.protein, Salivary Proteins, Salivary Cystatins, Electrophoresis, Polyacrylamide Gel, Female, alpha-Amylases, business, Stress, Psychological |
| الوصف: |
Context: Quantitative changes of salivary proteins due to acute stress were detected. Objective: To explore protein markers of stress in saliva of eight medical residents who performed emergency medicine simulations. Materials and methods: Saliva was collected before the simulations, after the simulations, and following morning upon waking. Proteins were separated by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), identified by mass spectrometry (MS), and relatively quantified by densitometry. Results: Salivary alpha-amylase and S–type cystatins significantly increased, while the ∼26 kDa and low-molecular weight (MW) (Discussion and conclusion: Alpha-amylase and cystatins are potential salivary markers of acute stress, but further validation should be performed using larger sample populations. |
| DOI: |
10.6084/m9.figshare.4587418 |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489b509653adf8bb6e8541f5b3c1e4f5 |
| Rights: |
OPEN |
| رقم الانضمام: |
edsair.doi.dedup.....489b509653adf8bb6e8541f5b3c1e4f5 |
| قاعدة البيانات: |
OpenAIRE |