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CC chemokine receptor 5 antagonist alleviates inflammation by regulating IFN-γ/IL-10 and STAT4/Smad3 signaling in a mouse model of autoimmune encephalomyelitis

التفاصيل البيبلوغرافية
العنوان: CC chemokine receptor 5 antagonist alleviates inflammation by regulating IFN-γ/IL-10 and STAT4/Smad3 signaling in a mouse model of autoimmune encephalomyelitis
المؤلفون: Sheikh F. Ahmad, Ahmed Nadeem, Mushtaq A. Ansari, Saleh A. Bakheet, Mudassar Shahid, Haneen A. Al-Mazroua, Homood M. As Sobeai, Abdullah F. Alasmari, Mohammed M. Alanazi, Abdullah S. Alhamed, Abdullah A. Aldossari, Sabry M. Attia
المصدر: Cellular immunology. 379
سنة النشر: 2022
مصطلحات موضوعية: Inflammation, Encephalomyelitis, Autoimmune, Experimental, Multiple Sclerosis, Immunology, Interleukin-17, Forkhead Transcription Factors, Mice, Inbred Strains, Nuclear Receptor Subfamily 1, Group F, Member 3, STAT4 Transcription Factor, Interleukin-10, Mice, Inbred C57BL, Disease Models, Animal, Interferon-gamma, Mice, Transforming Growth Factor beta, CCR5 Receptor Antagonists, Animals, Encephalomyelitis
الوصف: Multiple sclerosis (MS) is an immunopathological disease that causes demyelination and recurrent episodes of T cell-mediated immune attack in the central nervous system. Experimental autoimmune encephalomyelitis (EAE) is a well-established mouse model of MS. The roles of T cells in MS/EAE have been well investigated, but little is known about the role of CCR5
تدمد: 1090-2163
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4831e8380cbbfd2493fb049761749e03
https://pubmed.ncbi.nlm.nih.gov/35872534
Rights: CLOSED
رقم الانضمام: edsair.doi.dedup.....4831e8380cbbfd2493fb049761749e03
قاعدة البيانات: OpenAIRE
الوصف
تدمد:10902163