Identical lesion morphology in primary progressive and relapsing–remitting MS –an ultrahigh field MRI study
| العنوان: | Identical lesion morphology in primary progressive and relapsing–remitting MS –an ultrahigh field MRI study |
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| المؤلفون: | Joseph Kuchling, Caren Ramien, Berit Rosche, Thoralf Niendorf, Lutz Harms, Friedemann Paul, Jan Dörr, Tim Sinnecker, Ivan Bozin, Jens Wuerfel |
| المصدر: | Multiple Sclerosis Journal. 20:1866-1871 |
| بيانات النشر: | SAGE Publications, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Adult, Male, Pathology, medicine.medical_specialty, Morphology (linguistics), Ultrahigh field, Disease course, Cohort Studies, Primary progressive, Lesion, Multiple Sclerosis, Relapsing-Remitting, medicine, Humans, Gray Matter, Cerebral Cortex, business.industry, Multiple sclerosis, Brain, Middle Aged, Multiple Sclerosis, Chronic Progressive, medicine.disease, Magnetic Resonance Imaging, White Matter, Hyperintensity, Neurology, Relapsing remitting, Disease Progression, Female, Neurology (clinical), medicine.symptom, business |
| الوصف: | Potential differences between primary progressive (PP) and relapsing–remitting (RR) multiple sclerosis (MS) have been controversially discussed. In this study, we compared lesion morphology and distribution in patients with PPMS and RRMS (nine in each group) using 7 T MRI. We found that gray and white matter lesions in PPMS and RRMS patients did not differ in their respective morphological characteristics (e.g. perivascular p = 0.863, hypointense rim p = 0.796, cortical lesion count p = 0.436). Although limited by a small sample size, our study results suggest that PPMS and RRMS, despite differences in disease course and clinical characteristics, exhibit identical lesion morphology under ultrahigh field MRI. |
| تدمد: | 1477-0970 1352-4585 |
| DOI: | 10.1177/1352458514531084 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4822b21b6a73cc966b4bbf7e788cde2e https://doi.org/10.1177/1352458514531084 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....4822b21b6a73cc966b4bbf7e788cde2e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14770970 13524585 |
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| DOI: | 10.1177/1352458514531084 |