Early clinical and procedural outcomes in large series of 34-mm self-expanding transcatheter aortic valve replacement
| العنوان: | Early clinical and procedural outcomes in large series of 34-mm self-expanding transcatheter aortic valve replacement |
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| المؤلفون: | Khawaja Afzal Ammar, Payal Sharma, Daniel P. O'Hair, Ahmed Dalmar, Zuber Sherefa Ali, Suhail Allaqaband, Tadele W. Mengesha, Bijoy K. Khandheria, Renuka Jain, Tanvir Bajwa |
| المصدر: | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac AngiographyInterventionsREFERENCES. 96(4) |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Aortic valve, Male, medicine.medical_specialty, Time Factors, Transcatheter aortic, Sedation, medicine.medical_treatment, 030204 cardiovascular system & hematology, Prosthesis Design, Prosthesis, Severity of Illness Index, Perimeter, Transcatheter Aortic Valve Replacement, 03 medical and health sciences, 0302 clinical medicine, Postoperative Complications, Valve replacement, Risk Factors, medicine, Humans, Radiology, Nuclear Medicine and imaging, 030212 general & internal medicine, Hospital Mortality, Aged, Retrospective Studies, Aged, 80 and over, Framingham Risk Score, business.industry, General Medicine, Aortic Valve Stenosis, Recovery of Function, Surgery, medicine.anatomical_structure, Treatment Outcome, Cardiothoracic surgery, Aortic Valve, Heart Valve Prosthesis, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, business |
| الوصف: | Objectives We aimed to evaluate early clinical and procedural outcomes with the 34-mm Evolut R transcatheter aortic valve replacement (TAVR) prosthesis. Background The 34-mm Evolut R (Medtronic, Minneapolis, MN) self-expanding TAVR prosthesis was designed to treat patients with larger annuli. Methods Clinical, demographic, procedural, and echocardiographic data on consecutive patients who underwent TAVR with a 34-mm Evolut R prosthesis at our institution were collected and analyzed. Results One hundred ninety-six patients underwent TAVR with this prosthesis from November 2016 to July 2018, a majority (n = 188, 96%) through transfemoral access and with conscious sedation (n = 182, 93%). Mean age, Society of Thoracic Surgery risk score, and follow-up were 82 ± 8 years, 5.4 ± 5%, and 8.2 ± 5.3 months, respectively. Mean aortic valve (AV) peak velocity was 4.0 ± 0.6 m/s, mean AV gradient was 38 ± 13 mmHg, AV area was 0.79 ± 0.23 cm2 ; calcium score was 3,503 ± 1,970 Agatston units, and perimeter was 85 ± 4.3 mm. Device implantation was successful in all but one patient. Postprocedure mean AV peak velocity, AV mean gradient, and AV area were 1.9 ± 0.4 m/s, 7 ± 3 mmHg, and 2.6 ± 0.7 cm2 , respectively. New pacemaker requirement rate was 16%, and moderate paravalvular leak was present in six patients (3%), which improved to mild in three patients at 6-month follow-up. In-hospital, 30-day, 6-month, and 12-month survival rates were 98%, 96% (hospital discharge), 96% (30-day), 89% (6-month), and 83% (12-month). Conclusion These data demonstrate high success and good procedural, echocardiographic, and clinical outcomes of 34-mm Evolut R in patients with large annuli. |
| تدمد: | 1522-726X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4683c2c55d54917051dc2ab98c3de920 https://pubmed.ncbi.nlm.nih.gov/31797524 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....4683c2c55d54917051dc2ab98c3de920 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1522726X |
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