Risk of hospitalization for common neonatal morbidities in preterm and term infants: assessing the impact of one or more major congenital anomalies
| العنوان: | Risk of hospitalization for common neonatal morbidities in preterm and term infants: assessing the impact of one or more major congenital anomalies |
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| المؤلفون: | Samantha St. Laurent, Janet R Hardy, Mara G. Coyle, Jeanne M. Pimenta, Shibani Pokras, Harish M. Sehdev, Libby Black |
| المصدر: | Journal of Perinatology. 39:1602-1610 |
| بيانات النشر: | Springer Science and Business Media LLC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, Risk, medicine.medical_specialty, Pediatrics, Term Birth, Infant, Premature, Diseases, Infant, Newborn, Diseases, Congenital Abnormalities, Sepsis, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, Epidemiology, medicine, Humans, 030212 general & internal medicine, Neonatal health, Retrospective Studies, business.industry, Infant, Newborn, Obstetrics and Gynecology, Apnea, Retrospective cohort study, medicine.disease, Hospitalization, Increased risk, Pediatrics, Perinatology and Child Health, Cohort, population characteristics, Female, medicine.symptom, business, Infant, Premature |
| الوصف: | To analyze the impact of ≥1 major congenital anomaly (CA) on risk and hospitalization for common neonatal morbidities. Retrospective infant cohort: 241,033 preterm and 3,446,156 term singletons in the US Premier Healthcare database (2006–2013) with up to 1-year follow-up. Discharge records were searched for ≥1 CA and neonatal morbidities. Five morbidities demonstrated strong increasing rates as GA decreased. RRs in preterm infants with CAs relative to those without CAs were: RDS (2.17, 95% CI 2.14–2.21), sepsis (2.42, 95% CI 2.37–2.46), apnea (2.04, 95% CI 2.01–2.07), infectious diseases (2.37, 95% CI 2.34–2.41), and hyperbilirubinemia (1.25, 95% CI 1.24–1.26). Median length of NICU stay (days) was consistently longer in infants with ≥1 CA relative to infants without CA during each GA period. Preterm infants with ≥1 major CA have increased risk of hospitalization for common morbidities, implying compromised neonatal health regardless of CA type. |
| تدمد: | 1476-5543 0743-8346 |
| DOI: | 10.1038/s41372-019-0460-4 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c10ea79eeb0730dedbaf3dbbb7cbcb0 https://doi.org/10.1038/s41372-019-0460-4 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....3c10ea79eeb0730dedbaf3dbbb7cbcb0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14765543 07438346 |
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| DOI: | 10.1038/s41372-019-0460-4 |