Flavoenzyme-Catalyzed Oxygenations and Oxidations of Phenolic Compounds
| العنوان: | Flavoenzyme-Catalyzed Oxygenations and Oxidations of Phenolic Compounds |
|---|---|
| المؤلفون: | Marco W. Fraaije, Mariëlle J. H. Moonen, Colja Laane, Ivonne M.C.M. Rietjens, Willem J. H. van Berkel |
| المساهمون: | Stratingh Institute of Chemistry |
| المصدر: | Advanced Synthesis & Catalysis, 344(10), 1023-1035. WILEY-V C H VERLAG GMBH Advanced Synthesis and Catalysis, 344, 1023-1035 Advanced Synthesis and Catalysis 344 (2002) |
| بيانات النشر: | Wiley, 2002. |
| سنة النشر: | 2002 |
| مصطلحات موضوعية: | Vanillyl-alcohol oxidase, Biochemie, phenols, Toxicology, stereoselectivity, PSEUDOMONAS-AZELAICA HBP1, Biochemistry, Catalysis, 2-HYDROXYBIPHENYL 3-MONOOXYGENASE, chemistry.chemical_compound, Regioselectivity, Phenols, flavoprotein, PARA-HYDROXYBENZOATE HYDROXYLASE, CANDIDA-PARAPSILOSIS CBS604, Organic chemistry, CRYSTAL-STRUCTURE, Monooxygenase, monooxygenase, Flavin-dependent, Toxicologie, VLAG, chemistry.chemical_classification, Oxidase test, aromatic hydroxylation, Chemistry, BAEYER-VILLIGER OXIDATION, Mutagenesis, oxidase, Stereoselectivity, General Medicine, Mineralization (soil science), General Chemistry, Flavoprotein, Baeyer–Villiger oxidation, 4-HYDROXYBENZOATE 1-HYDROXYLASE, FAD-DEPENDENT MONOOXYGENASE, Enzyme, VANILLYL-ALCOHOL OXIDASE, ESCHERICHIA-COLI, regioselectivity, Aromatic hydroxylation, flavin-dependent, Oxidase |
| الوصف: | Flavin-dependent monooxygenases and oxidases play an important role in the mineralization of phenolic compounds. Because of their exquisite regioselectivity and stereoselectivity, these enzymes are of interest for the biocatalytic production of fine chemicals and food ingredients. In our group, we have characterized several flavoenzymes that act on phenolic compounds, including 4-hydroxybenzoate 3-hydroxylase, 3-hydroxyphenylacetate 6-hydroxylase, 4-hydroxybenzoate 1-hydroxylase (decarboxylating), hydroquinone hydroxylase, 2-hydroxybiphenyl 3-monooxygenase, phenol hydroxylase, 4-hydroxyacetophenone monooxygenase and vanillyl-alcohol oxidase. The catalytic properties of these enzymes are reviewed here, together with insights obtained from site-directed and random mutagenesis. |
| وصف الملف: | application/pdf; application/octet-stream |
| تدمد: | 1615-4169 1615-4150 |
| DOI: | 10.1002/1615-4169(200212)344:10<1023::aid-adsc1023>3.0.co;2-t |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b629ba6bd2e40c5b44e4d7eb4a05eab https://doi.org/10.1002/1615-4169(200212)344:10<1023::aid-adsc1023>3.0.co;2-t |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....3b629ba6bd2e40c5b44e4d7eb4a05eab |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16154169 16154150 |
|---|---|
| DOI: | 10.1002/1615-4169(200212)344:10<1023::aid-adsc1023>3.0.co;2-t |