Acrodermatitis chronica atrophicans: clinical and microbiological characteristics of a cohort of 693 Slovenian patients
| العنوان: | Acrodermatitis chronica atrophicans: clinical and microbiological characteristics of a cohort of 693 Slovenian patients |
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| المؤلفون: | Vera Maraspin, Lara Lusa, T. Cerar Kišek, Katarina Ogrinc, Eva Ružić-Sabljić, Franc Strle |
| المصدر: | Journal of Internal Medicine. 290:335-348 |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, Male, 0301 basic medicine, medicine.medical_specialty, Constitutional symptoms, Slovenia, Arthritis, 030204 cardiovascular system & hematology, Borrelia afzelii, medicine.disease_cause, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Borrelia burgdorferi Group, Arthropathy, Internal Medicine, medicine, Humans, Aged, Paresis, Lyme Disease, business.industry, Acrodermatitis, Middle Aged, medicine.disease, Dermatology, 030104 developmental biology, Peripheral neuropathy, Cohort, Female, Atrophy, medicine.symptom, business, Acrodermatitis chronica atrophicans |
| الوصف: | BACKGROUND Information on large groups of patients with acrodermatitis chronica atrophicans (ACA) is limited. METHODS We assessed clinical and microbiological characteristics of patients with ACA diagnosed at a single medical centre and compared findings in periods 1991-2004 vs. 2005-2018. The cohort is representative of Slovenian ACA patients. RESULTS We assessed 693 patients: 461 females and 232 males, with median age of 64 years. Median duration of ACA before diagnosis was 12 months. In all but 2 patients, the skin lesions were located on extremities, more often on the lower (70.0%) than the upper (45.2%), bilaterally in 42.4%. Reddish-blue discoloration, swelling, thinning and wrinkling of skin were present in 95.2%, 28.1%, 46.4% and 20.5% of patients, respectively. Overall, 64.4% of patients reported constitutional symptoms, 23.1% had local symptoms, and 20.8% had symptoms/signs of peripheral neuropathy. Nodules, arthritis, joint deformity, muscle atrophy and paresis were rare ( |
| تدمد: | 1365-2796 0954-6820 |
| DOI: | 10.1111/joim.13266 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37530651b9ef56b911f98e8514c77cdc https://doi.org/10.1111/joim.13266 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....37530651b9ef56b911f98e8514c77cdc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13652796 09546820 |
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| DOI: | 10.1111/joim.13266 |