Characterization Of Tetracycline Resistance Of Salmonella Enterica Subspecies Enterica Serovar Infantis Isolated From Poultry In The Northern Part Of Serbia
| العنوان: | Characterization Of Tetracycline Resistance Of Salmonella Enterica Subspecies Enterica Serovar Infantis Isolated From Poultry In The Northern Part Of Serbia |
|---|---|
| المؤلفون: | Dejan Vidanović, Maja Velhner, Dejan Krnjaić, Igor Stojanov, Dubravka Milanov, Ljiljana Suvajdžić, Dalibor Todorović |
| المصدر: | Acta Veterinaria-Beograd Acta Veterinaria, Vol 65, Iss 4, Pp 548-556 (2015) |
| بيانات النشر: | Walter de Gruyter GmbH, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | 2. Zero hunger, Serotype, Antiinfective agent, General Veterinary, biology, Nalidixic acid, Tetracycline, poultry, Veterinary medicine, tetr gene, Drug resistance, biochemical phenomena, metabolism, and nutrition, Subspecies, biology.organism_classification, Microbiology, Salmonella enterica, teta gene, SF600-1100, medicine, salmonella infantis, transposone tn1721, Disease transmission, tetracycline, medicine.drug |
| الوصف: | Resistance to tetracycline was studied in Salmonella Infantis isolated from 28 poultry farms in the Northern part of Serbia (The Autonomous Province of Vojvodina). A total of 18 isolates were resistant to nalidixic acid (NAL) and tetracycline (TET). The minimal inhibitory concentration (MIC) to TET, ranged from 1-256 mg/L. Namely, 13 isolates exhibited MIC to TET at 256 mg/L, in four of the isolates, the MIC was 128 mg/L and one isolate had MIC 64 mg/L. Ten isolates were exhibiting a MIC of 1mg/L. It was evident that Salmonella Infantis had also spread to breeders and layers. In this work, we detected the tetA gene and the corresponding tetR gene (encoding the repressor protein) as well as the truncated transposon Tn1721, which are responsible for the resistance to TET. The presence of the non conjugative transposons from the conjugative plasmid has facilitated the spread of resistance to TET in Salmonella. It was concluded that higher biosecurity practice in poultry farming presents the best option to eliminate infections caused by Salmonella spp. from poultry flocks in Serbia. A rational use of antimicrobials is necessary to prevent any further spread of Salmonella Infantis resistant clones. |
| تدمد: | 1820-7448 |
| DOI: | 10.1515/acve-2015-0046 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d4d633bd7fc59632d255416b1e1dbe https://doi.org/10.1515/acve-2015-0046 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....36d4d633bd7fc59632d255416b1e1dbe |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18207448 |
|---|---|
| DOI: | 10.1515/acve-2015-0046 |