Reduced number of hemidesmosomes in the corneal epithelium of diabetics with proliferative vitreoretinopathy
| العنوان: | Reduced number of hemidesmosomes in the corneal epithelium of diabetics with proliferative vitreoretinopathy |
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| المؤلفون: | Brigitte Baumgartner, Peter M. Leuenberger, Moïra Bumbacher, Cyrus Tabatabay |
| المصدر: | Graefe's Archive for Clinical and Experimental Ophthalmology. 226:389-392 |
| بيانات النشر: | Springer Science and Business Media LLC, 1988. |
| سنة النشر: | 1988 |
| مصطلحات موضوعية: | Proliferative vitreoretinopathy, Pathology, medicine.medical_specialty, Eye Diseases, medicine.medical_treatment, Vitrectomy, Basement Membrane, Epithelium, Cornea, Cellular and Molecular Neuroscience, Basal (phylogenetics), medicine, Humans, Corneal epithelium, Basement membrane, Diabetic Retinopathy, business.industry, Hemidesmosome, Cell Membrane, Desmosomes, medicine.disease, eye diseases, Sensory Systems, Vitreous Body, Ophthalmology, medicine.anatomical_structure, sense organs, business |
| الوصف: | Morphometry on transmission electron micrographs of the hemidesmosomal width was related to the length of the basal plasmalemma in corneal epithelium biopsy specimens. The basal plasmalemma length occupied by hemidesmosomes showed a mean fraction of 0.227 in eight patients undergoing cataract extraction or vitrectomy for diabetic proliferative vitreoretinopathy. In seven non-diabetic control patients of comparable age and sex undergoing cataract or pterygium surgery, 0.412 of the basal plasmalemma was covered by hemidesmosomes. A reduction in hemidesmosomes (P less than 0.001) may contribute to a weakness in the adhesion of diabetic corneal epithelium to the underlying stroma. |
| تدمد: | 1435-702X 0721-832X |
| DOI: | 10.1007/bf02172973 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36004eeae2d147fe2b59e0121512b4db https://doi.org/10.1007/bf02172973 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....36004eeae2d147fe2b59e0121512b4db |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1435702X 0721832X |
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| DOI: | 10.1007/bf02172973 |