A Model of Hyperhomocysteine-Induced Endothelial Dysfunction in Rats
| العنوان: | A Model of Hyperhomocysteine-Induced Endothelial Dysfunction in Rats |
|---|---|
| المؤلفون: | E. A. Konovalova, O. O. Novikov, Liliya V. Korokina, M. V. Korokin, V. A. Ragulina, Vladimir V. Gureev, Gudyrev Os, Lyudmila M. Danilenko, Mikhail V. Pokrovskiy, A. S. Belous, T. A. Denisyuk |
| المصدر: | Bulletin of Experimental Biology and Medicine. 152:213-215 |
| بيانات النشر: | Springer Science and Business Media LLC, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Hyperhomocysteinemia, Methionine, Endothelium, Homocysteine, business.industry, General Medicine, Pharmacology, medicine.disease, General Biochemistry, Genetics and Molecular Biology, Rats, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, medicine, Animals, Endothelium, Vascular, Vascular Diseases, Vascular pathology, Endothelial dysfunction, business |
| الوصف: | Intragastric methionine (3 g/kg daily for 7 days) elevates homocysteine concentration and increases the endothelial dysfunction coefficient. This protocol of methionine treatment is an adequate model of hyperhomocysteine-induced endothelial dysfunction and can be used for studies of the endothelio- and cardioprotective effects of drugs. |
| تدمد: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-011-1491-9 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356b96b216b60eccf1022fc2963177ad https://doi.org/10.1007/s10517-011-1491-9 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....356b96b216b60eccf1022fc2963177ad |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15738221 00074888 |
|---|---|
| DOI: | 10.1007/s10517-011-1491-9 |