التفاصيل البيبلوغرافية
| العنوان: |
Evaluation of hepatic perfusion in the liver graft using fluorescence imaging with indocyanine green |
| المؤلفون: |
Junichi Kaneko, Yoshihiro Sakamoto, Junichi Arita, Kiyoshi Hasegawa, Takeaki Ishizawa, Nobuhisa Akamatsu, Yoshikuni Kawaguchi, Norihiro Kokudo |
| المصدر: |
International Journal of Surgery Case Reports |
| بيانات النشر: |
The Authors. Published by Elsevier Ltd. |
| مصطلحات موضوعية: |
Fluorescence imaging technique, medicine.medical_specialty, Fluorescence-lifetime imaging microscopy, Graft dysfunction, Pathology, genetic structures, medicine.medical_treatment, ICG, indocyanine green, Liver transplantation, LT, liver transplantation, behavioral disciplines and activities, Article, D-IOUS, Doppler intraoperative ultrasonography, chemistry.chemical_compound, mental disorders, Medicine, FI, fluorescence intensity, business.industry, PVT, portal vein thrombosis, food and beverages, medicine.disease, Portal vein thrombosis, eye diseases, Indocyanine green, Liver graft, Fluorescence intensity, Living-donor liver transplantation, surgical procedures, operative, chemistry, Surgery, Radiology, business, human activities, Perfusion |
| الوصف: |
Highlights • Portal vein thrombosis after liver transplantation is one of serious complications. • Indocyanine green (ICG)-fluorescence imaging can visualize the impaired perfusion or congestive area on the liver graft surface clearly. • ICG-fluorescence imaging can visualize regions with impaired hepatic perfusion during liver translantation in addition to visualization of hepatic flows of reconstructed vessels and evaluation of regions with venous occlusion.
Introduction Portal vein thrombosis (PVT) after liver transplantation (LT) is one of serious complications and reportedly ranges from 2% to 13%. PVT impairs the blood perfusion to the grafts and causes the graft dysfunction. Presentation of case A 60-year-old female underwent living-donor LT with the left liver graft for end-stage liver disease related to chronic hepatitis C. After reperfusion, Indocyanine green (ICG)-fluorescence imaging was performed to confirm the graft perfusion, which pointed out an insufficient perfusion on the surface of segment 4. Following intraoperative ultrasonography revealed thrombus in the portal vein of segment 4, which was successfully removed by heparinized saline flush. Discussion The most of patients with PVT developed graft failure and resulted in retransplantation. This enhances the importance of the surveillance for PVT in the postoperative period as well as the intraoperative period. However, the modality to identify PVT during surgery is limited mainly to intraoperative ultrasound. ICG-fluorescence imaging can visualize regions with impaired hepatic perfusion due to PVT in real time during LT in addition to visualization of hepatic flows of reconstructed vessels and evaluation of regions with venous occlusion. Conclusion ICG-fluorescence imaging can be simply performed with single ICG injection and is expected to have potential roles to enhance the safety of LT. |
| اللغة: |
English |
| تدمد: |
2210-2612 |
| DOI: |
10.1016/j.ijscr.2015.07.031 |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a4939675f85cd1afe46f25d1bbb467 |
| Rights: |
OPEN |
| رقم الانضمام: |
edsair.doi.dedup.....34a4939675f85cd1afe46f25d1bbb467 |
| قاعدة البيانات: |
OpenAIRE |