Letter to the editor: Comments on Schalich et al. (2021), Colostrum testing with Brix is a valuable on-farm tool. doi.org/10.193/jas/skab083
| العنوان: | Letter to the editor: Comments on Schalich et al. (2021), Colostrum testing with Brix is a valuable on-farm tool. doi.org/10.193/jas/skab083 |
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| المؤلفون: | Jason Lombard, James Quigley, Deborah Haines, Frank Garry, Tom Earleywine, Natalie Urie, Manuel Chamorro, Sondra Godden, Sheila McGuirk, Geof Smith, Chelsey Shivley, Dan Catherman, A Jud Heinrichs, Robert James, John Maas, Keith Sterner, Don Sockett |
| المصدر: | J Anim Sci |
| بيانات النشر: | Oxford University Press (OUP), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Immunodiffusion, Farms, Colostrum, Animal Health and Well Being, food and beverages, General Medicine, Body Fluids, Kinetics, Dairying, Milk, fluids and secretions, Animals, Newborn, Pregnancy, Immunoglobulin G, Genetics, Animals, Cattle, Female, Animal Science and Zoology, News and Views, Food Science |
| الوصف: | Neonatal calf survival and health is predominantly dependent on sufficient consumption of immunoglobulin G (IgG) and the resulting transfer of passive immunity (TPI). In this study, we investigate the potential for continued IgG secretion and temporal kinetics of mammary IgG output in sequential milkings performed at 0, 4, 16, 28, 40, and 52 hr postcalving in Holstein dairy cows. For colostrum (0 hr), we also scrutinize the relationships between IgG concentration, volume, refractometer readings (Bx values, Brix) and concentration of sugars (lactose and glucose). Mammary transcripts postpartum (0 hr) indicated that active IgG secretion continues beyond the first milking (colostrum; n = 4 to 5). IgG measurements at the different timepoints indicated that colostrum represents only 25.1% of the total IgG produced across the 6 sequential milking timepoints, with a substantial 48.9% being secreted into transition milk over the next 3 timepoints (4-, 6-, and 28-hr) combined. The differences on the basis of IgG concentrations across 0-, 4-, and 16-hr milking timepoints were not statistically significant (P = 0.1522; n = 9). For colostrum, volume remained highly variable, even with induced let-down prior to milking (n = 27). Nonetheless, colostrum IgG secretion was significantly co-regulated with volume (R(2) = 0.915; P < 0.001; n = 18), an association that was stronger than that measured for lactose (R(2) = 0.803; P < 0.001; n = 18) and glucose (R(2) = 0.467; P = 0.002; n = 17). Comparing colostrum Bx values to absolute IgG concentrations showed no correlation (R(2) = 0.127; P = 0.07; n = 27); biochemical separation of colostrum components indicated that both proteins and nonprotein solutes could affect Bx values (P < 0.0001 for both; n = 5). This suggests that Bx values do not reasonably indicate IgG concentration to serve as a measure of colostrum quality. Additionally, our finding that early transition milk (4-, 6-, and 28-hr) can contribute substantially more IgG than colostrum forces a rethink of existing feeding paradigms and means to maximize TPI in calves. Collectively, our results reveal the remarkable value of early transition milk and caveats to colostrum assessments that could advance application in enhancing neonatal calf health. |
| تدمد: | 1525-3163 0021-8812 |
| DOI: | 10.1093/jas/skac119 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3437e3def088f7b21b1d804df0677f12 https://doi.org/10.1093/jas/skac119 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....3437e3def088f7b21b1d804df0677f12 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15253163 00218812 |
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| DOI: | 10.1093/jas/skac119 |