التفاصيل البيبلوغرافية
| العنوان: |
Epidemiology of multiple sclerosis in western Herzegovina |
| المؤلفون: |
Vlatko Šulentić, Juraj Sepčić, Tonka Jurišić, Borut Peterlin, Dražena Martinović Mamić, Miljenko Kapović, Inge Klupka-Sarić, Adnan Burina, Smiljana Ristić, Eris Materljan |
| المصدر: |
Clinical Neurology and Neurosurgery. 109:779-783 |
| بيانات النشر: |
Elsevier BV, 2007. |
| سنة النشر: |
2007 |
| مصطلحات موضوعية: |
Adult, Male, medicine.medical_specialty, Multiple Sclerosis, Adolescent, Central nervous system disease, Age Distribution, Internal medicine, Epidemiology, Prevalence, medicine, Humans, Age of Onset, Sex Distribution, Aged, Retrospective Studies, Bosnia and Herzegovina, business.industry, Incidence, Multiple sclerosis, Medical record, Incidence (epidemiology), Retrospective cohort study, General Medicine, Middle Aged, medicine.disease, Confidence interval, Surgery, multiple sclerosis, prevalence, incidence, Herzegovina, Europe, Female, Neurology (clinical), Age of onset, business |
| الوصف: |
Objectives: To determine epidemiological rates of multiple sclerosis (MS) in western Herzegovina. Patients and methods: We analysed data from 81 MS patients (49 females, 32 males) on the prevalence day, 31 December 2003. Patient information was obtained from a search of all available medical records from the period 1994–2003 in the investigated area. Results: Crude prevalence of MS was 27/100,000 (95% confidence interval (CI) 20–34). Prevalence was highest in the mountainous municipality of Posuy (56/100,000) and lowest in the coastal municipality of Neum (0 incidence). The annual incidence of MS was 1.6/100,000 (95% CI 0–3.3). The female/male ratio of MS was 1.5. The mean age of the patients on prevalence day was 40.0 ± 11.6 years, and the mean age at disease onset was 31.0 ± 7.1 years. Eight (10%) of the patients had a first-degree relative with MS. The primary progressive (PP) disease course was observed only in females. Visual symptoms were the initial symptom of MS in 6 (7%) of the patients. Conclusions: Western Herzegovina is an area of moderate risk for MS, and the distribution of MS in western Herzegovina is heterogeneous. PP-MS occurred only in females, and involvement of the visual pathways as the initial symptom of MS was low. © 2007 Elsevier B.V. All rights reserved. |
| تدمد: |
0303-8467 |
| DOI: |
10.1016/j.clineuro.2007.07.014 |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e8bb937d8abf614f49723ec41b8170
https://doi.org/10.1016/j.clineuro.2007.07.014 |
| Rights: |
CLOSED |
| رقم الانضمام: |
edsair.doi.dedup.....31e8bb937d8abf614f49723ec41b8170 |
| قاعدة البيانات: |
OpenAIRE |