Significance of cancer stroma for bone destruction in oral squamous cell carcinoma using different cancer stroma subtypes
| العنوان: | Significance of cancer stroma for bone destruction in oral squamous cell carcinoma using different cancer stroma subtypes |
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| المؤلفون: | Qiusheng, Shan, Kiyofumi, Takabatake, Hotaka, Kawai, May Wathone, Oo, Yasunori, Inada, Shintaro, Sukegawa, Shigeko, Fushimi, Keisuke, Nakano, Hitoshi, Nagatsuka |
| المصدر: | Oncology Reports. 47 |
| بيانات النشر: | Spandidos Publications, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Cancer Research, Oncology, Head and Neck Neoplasms, Squamous Cell Carcinoma of Head and Neck, Cell Line, Tumor, RANK Ligand, Carcinoma, Squamous Cell, Tumor Microenvironment, Humans, Osteoclasts, Mouth Neoplasms, General Medicine, Bone Resorption |
| الوصف: | Stromal cells in the tumor microenvironment (TME) can regulate the progression of numerous types of cancer; however, the bone invasion of oral squamous cell carcinoma (OSCC) has been poorly investigated. In the present study, the effect of verrucous SCC‑associated stromal cells (VSCC‑SCs), SCC‑associated stromal cells (SCC‑SCs) and human dermal fibroblasts on bone resorption and the activation of HSC‑3 osteoclasts |
| تدمد: | 1791-2431 1021-335X |
| DOI: | 10.3892/or.2022.8292 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fc05a188e2f0fb09be24d421a18497 https://doi.org/10.3892/or.2022.8292 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....30fc05a188e2f0fb09be24d421a18497 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17912431 1021335X |
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| DOI: | 10.3892/or.2022.8292 |