Could Diffusion-Weighted Imaging Detect Injured Bile Ducts of Ischemic-Type Biliary Lesions After Orthotopic Liver Transplantation?

التفاصيل البيبلوغرافية
العنوان: Could Diffusion-Weighted Imaging Detect Injured Bile Ducts of Ischemic-Type Biliary Lesions After Orthotopic Liver Transplantation?
المؤلفون: Hong Shan, Jing-jing Liu, Jin Wang, Zai-bo Jiang, Qi Zhang, Ying-ying Liang, Bing Hu
المصدر: American Journal of Roentgenology. 199:901-906
بيانات النشر: American Roentgen Ray Society, 2012.
سنة النشر: 2012
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Orthotopic liver transplantation, medicine.medical_treatment, Liver transplantation, Gastroenterology, Magnetic resonance angiography, Cholangiography, Cholestasis, Internal medicine, medicine, Humans, Radiology, Nuclear Medicine and imaging, In patient, cardiovascular diseases, Aged, Cholangiopancreatography, Endoscopic Retrograde, medicine.diagnostic_test, business.industry, General Medicine, Middle Aged, medicine.disease, Hyperintensity, Liver Transplantation, Diffusion Magnetic Resonance Imaging, Female, Bile Ducts, Radiology, business, Magnetic Resonance Angiography, Diffusion MRI
الوصف: The purpose of this article is to discuss whether diffusion-weighted imaging (DWI) shows new findings of injured bile ducts in patients with ischemic-type biliary lesions (ITBL) after orthotopic liver transplantation.Thirty-five transplant recipients with ITBL (ITBL group), 20 recipients without biliary abnormalities on MRCP (control group), and 20 volunteers who did not undergo liver transplantation (healthy group) underwent MRI, MRCP, and DWI examinations.Twenty-nine ITBL patients showed hyperintensity of bile ducts on DWI (82.9%, 29/35). However, only one case in the control group and no cases in the healthy group showed hyperintensity. The difference in the signal change of bile ducts on DWI between the ITBL and control groups was significant (p0.001). The high accuracy of MRCP and DWI were 96.4% (53/55) and 87.3 (48/55), respectively. In the ITBL group, two early ITBL patients showed "normality" of bile ducts on MRCP but hyperintensity of small bile ducts on DWI, except thirty-three patients showed irregular stenosis and dilatation of bile ducts on MRCP (94.3%, 33/35).MRCP is a noninvasive first-choice for clinical diagnosis of ITBL, mainly relying on morphologic abnormality of bile ducts. Hyperintensity of the bile ducts with ITBL patients on DWI might offer a method of noninvasively and sensitively detecting injured bile ducts, especially for early injuries, and may be helpful in detecting etiologic information of ITBL and as an effective supplement to MRCP in ITBL.
تدمد: 1546-3141
0361-803X
DOI: 10.2214/ajr.11.8147
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4e9b56f10ce6dcff1b8989959f09a0
https://doi.org/10.2214/ajr.11.8147
رقم الانضمام: edsair.doi.dedup.....2f4e9b56f10ce6dcff1b8989959f09a0
قاعدة البيانات: OpenAIRE
الوصف
تدمد:15463141
0361803X
DOI:10.2214/ajr.11.8147