The impact of long-term moderate level of vaccination coverage for epidemiology of varicella in Lu'an, China: should we change immunisation strategy now?
| العنوان: | The impact of long-term moderate level of vaccination coverage for epidemiology of varicella in Lu'an, China: should we change immunisation strategy now? |
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| المؤلفون: | Liang Zhang, Yao Wang, Wei Qin, Shaoyu Xie, Xiang-Mei Meng, Kaichun Li, Xiao-Kang Xu |
| المصدر: | Epidemiology and Infection |
| بيانات النشر: | Cambridge University Press, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0301 basic medicine, Male, medicine.medical_specialty, China, Vaccination Coverage, Varicella vaccine, Adolescent, Epidemiology, 030106 microbiology, Population, Epidemiological method, Disease Outbreaks, Chickenpox Vaccine, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, varicella, Chickenpox, medicine, Humans, 030212 general & internal medicine, education, Child, education.field_of_study, Original Paper, vaccine effectiveness, business.industry, Incidence (epidemiology), Incidence, Moderate level, Infant, Vaccination, Infectious Diseases, Vaccination coverage, Child, Preschool, Female, Immunization, business, Demography |
| الوصف: | As China implements the voluntary vaccination programme of one-dose of varicella vaccine (VarV) for decades, robust estimates of the impact of voluntary vaccination era on epidemiology of varicella are needed. We estimated the vaccination coverage (VC) of VarV by using surveillance data on immunisation. The descriptive epidemiological method was used to describe the changing epidemiology of varicella from 2007 to 2018. The screening method was used to estimate the vaccine effectiveness (VE) of VarV. The overall VC for VarV was 71.7%, ranged from 47.7% to 79.5% among 2008–2017 birth cohorts. In total, 16 660 varicella cases were reported during 2007–2018, the incidence increased from 10.0 cases per 100 000 population in 2007 to 65.2 cases per 100 000 population in 2018. A shift in age group of varicella was observed since 2012, with the age increased from 5–9 years to 10–14 years. The overall VE was 79.9%, and the VE increased from 60.1% in 2008 birth cohort to 96.2% in 2017 birth cohort. We found that the overall VE for VarV is moderate, but appears highly effective within 5 years after vaccination. In addition, a shift varicella infection to older ages has occurred at the long-term moderate level VC of one-dose VarV. Therefore, to contain the incidence of varicella and prevent any potential shift to older ages, the introduction of VarV into routine immunisation programme is likely needed in Lu'an. |
| اللغة: | English |
| تدمد: | 1469-4409 0950-2688 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aabf00168f2e29478cb7b8c6b28121e http://europepmc.org/articles/PMC7118725 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....2aabf00168f2e29478cb7b8c6b28121e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14694409 09502688 |
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