Bone remodelling is reduced by recovery from iron-deficiency anaemia in premenopausal women
| العنوان: | Bone remodelling is reduced by recovery from iron-deficiency anaemia in premenopausal women |
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| المؤلفون: | Ruth Blanco-Rojo, Gemma Mancebo Moreno, Ione Wright, M. Cristina Fernández, Ana M. Pérez-Granados, M. Pilar Vaquero, Laura Toxqui, Angel F. Remacha, Concepción de la Piedra |
| المصدر: | Digital.CSIC. Repositorio Institucional del CSIC instname |
| بيانات النشر: | Springer Science and Business Media LLC, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Adult, medicine.medical_specialty, Adolescent, Physiology, Anemia, Iron, Bone resorption, Biochemistry, Collagen Type I, Bone remodeling, N-terminal telopeptide, hemic and lymphatic diseases, Internal medicine, medicine, Humans, Ferrous Compounds, Bone Resorption, Vitamin D, Anemia, Iron-Deficiency, business.industry, Iron-deficiency anaemia, Case-control study, nutritional and metabolic diseases, General Medicine, Iron deficiency, medicine.disease, Peptide Fragments, VitaminD status, Procollagen peptidase, Endocrinology, Premenopause, Parathyroid Hormone, Case-Control Studies, Hematinics, Female, Menstruating women, Peptides, Bone turnover markers, business, Body mass index, Biomarkers, Procollagen, PTH |
| الوصف: | Iron-deficiency anaemia (IDA), one of the most common and widespread health disorders worldwide, affects fundamental metabolic functions and has been associated with deleterious effects on bone. Our aim was to know whether there are differences in bone remodelling between a group of premenopausal IDA women and a healthy group, and whether recovery of iron status has an effect on bone turnover markers. Thirty-five IDA women and 38 healthy women (control group) were recruited throughout the year. IDA women received pharmacological iron treatment. Iron biomarkers, aminoterminal telopeptide of collagen I (NTx), procollagen type 1 N-terminal propeptide (P1NP), 25-hydroxyvitamin D, and parathormone (PTH) were determined at baseline for both groups and after treatment with pharmacological iron for the IDA group. IDA subjects were classified as recovered (R) or non-recovered (nR) from IDA after treatment. NTx levels were significantly higher (p |
| تدمد: | 1877-8755 1138-7548 |
| DOI: | 10.1007/s13105-013-0266-3 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288d5e9e6fb84568e10770993b94eba2 https://doi.org/10.1007/s13105-013-0266-3 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....288d5e9e6fb84568e10770993b94eba2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18778755 11387548 |
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| DOI: | 10.1007/s13105-013-0266-3 |