Course and Outcome of Erythema Migrans in Pregnant Women
| العنوان: | Course and Outcome of Erythema Migrans in Pregnant Women |
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| المؤلفون: | Maja Pohar Perme, Vera Maraspin, Lara Lusa, Eva Ružić-Sabljić, Tanja Blejec, Franc Strle |
| المصدر: | Journal of Clinical Medicine Volume 9 Issue 8 Journal of clinical medicine, vol. 9, no. 8, 2364, 2020. Journal of Clinical Medicine, Vol 9, Iss 2364, p 2364 (2020) |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, gestacija, Constitutional symptoms, lcsh:Medicine, Article, 03 medical and health sciences, 0302 clinical medicine, gestation, Borrelia burgdorferi sensu lato, medicine, udc:616.9, 030212 general & internal medicine, erythema migrans, Lyme borreliosis, 0303 health sciences, Pregnancy, Fetus, pregnancy outcome, 030306 microbiology, Obstetrics, business.industry, lcsh:R, lymska borelioza, General Medicine, Odds ratio, medicine.disease, Ceftriaxone, Gestation, Erythema migrans, business, eritema migrans, medicine.drug |
| الوصف: | Information on Lyme borreliosis (LB) during pregnancy is limited. In the present study, the course and outcome of erythema migrans (EM) in 304 pregnant women, diagnosed in the period 1990&ndash 2015, was assessed and compared with that in age-matched non-pregnant women. The frequency of unfavorable outcome of pregnancies was also evaluated. The pregnant women reported constitutional symptoms less frequently than the non-pregnant women (22.4% vs. 37.2%, p < 0.001). Pregnant women diagnosed with EM later during pregnancy had a lower probability of reporting constitutional symptoms (odds ratio = 0.97 for 1-week difference in gestation week at diagnosis of EM, 95% CI: 0.94&ndash 0.99, p = 0.02). The outcome of pregnancy was unfavorable in 42/304 (13.8%) patients: preterm birth in 22/42 (52.4%), fetal/perinatal death in 10/42 (23.8%), and/or anomalies in 15/42 (35.7%). Several patients had potential explanation(s) for the unfavorable outcome. In conclusion, the course of early LB during pregnancy is milder than in age-matched non-pregnant women. The outcome of pregnancy with the treatment approach used in the present study (i.v. ceftriaxone 2 g once daily for 14 days) is favorable. |
| وصف الملف: | application/pdf; text/url |
| اللغة: | English |
| تدمد: | 2077-0383 |
| DOI: | 10.3390/jcm9082364 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a482b4630701b32c08dda1b15b585a |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....24a482b4630701b32c08dda1b15b585a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20770383 |
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| DOI: | 10.3390/jcm9082364 |