Dopamine agonists in prevention of ovarian hyperstimulation syndrome
العنوان: | Dopamine agonists in prevention of ovarian hyperstimulation syndrome |
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المؤلفون: | Patrik Stanić, Slavko Orešković, Lidija Beketić-Orešković, Miro Kasum, Davor Ježek, Hrvoje Vrcic, Marijeta Pekez |
المصدر: | Gynecological Endocrinology. 30:845-849 |
بيانات النشر: | Informa UK Limited, 2014. |
سنة النشر: | 2014 |
مصطلحات موضوعية: | medicine.medical_specialty, Cabergoline, Dopamine agonist, ovarian hyperstimulation syndrome, prevention, Endocrinology, Diabetes and Metabolism, Ovarian hyperstimulation syndrome, Placebo, Ovarian Hyperstimulation Syndrome, Endocrinology, Ovulation Induction, Dopamine, Internal medicine, medicine, Humans, Ergolines, Bromocriptine, business.industry, Quinagolide, Obstetrics and Gynecology, medicine.disease, Regimen, Dopamine Agonists, Aminoquinolines, Female, business, medicine.drug |
الوصف: | The aim of this review is to analyze the efficacy of different dopamine agonists in the prevention of ovarian hyperstimulation syndrome (OHSS). Cabergoline, quinagolide and bromocriptine are the most common dopamine agonists used. There are wide clinical variations among the trials in the starting time (from the day of human chorionic gonadotrophin (hCG) to the day following oocyte retrieval) ; the duration of the treatment (4-21 days), the dose of cabergoline (0.5 mg or 0.25 mg orally) and in the regimens used. At present, the best known effective regimen is 0.5 mg of cabergoline for 8 days or rectal bromocriptine at a daily dose of 2.5 mg for 16 days. Dopamine agonists have shown significant evidences of their efficacy in the prevention of moderate and early-onset OHSS (9.41%), compared with a placebo (21.45%), which cannot be confirmed for the treatment of late OHSS. It would be advisable to start with the treatment on the day of hCG injection or preferably a few hours earlier. The use of dopamine agonists should be indicated in patients at high risk of OHSS, as well as in patients with a history of previous OHSS even without evident signs of the syndrome. |
تدمد: | 1473-0766 0951-3590 |
DOI: | 10.3109/09513590.2014.943716 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2364194223823297e7d735e4db6ee905 https://doi.org/10.3109/09513590.2014.943716 |
Rights: | CLOSED |
رقم الانضمام: | edsair.doi.dedup.....2364194223823297e7d735e4db6ee905 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 14730766 09513590 |
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DOI: | 10.3109/09513590.2014.943716 |