Legionella quinlivanii strain isolated from a human: A case report and whole genome sequencing analysis

التفاصيل البيبلوغرافية
العنوان: Legionella quinlivanii strain isolated from a human: A case report and whole genome sequencing analysis
المؤلفون: Cindy Lalancette, Kathryn Bernard, Eric Fournier, Jacques Malo, Jean-Michel Leduc, Simon Lévesque, Sébastien P. Faucher, Joseph Saoud, Ana Luisa Pacheco, Christine Martineau
المصدر: J Assoc Med Microbiol Infect Dis Can
بيانات النشر: University of Toronto Press, 2020.
سنة النشر: 2020
مصطلحات موضوعية: Microbiology (medical), Whole genome sequencing, 0303 health sciences, Strain (chemistry), biology, medicine.diagnostic_test, 030306 microbiology, biology.organism_classification, 16S ribosomal RNA, Microbiology, 03 medical and health sciences, Infectious Diseases, Bronchoalveolar lavage, Lavage bronchoalveolaire, Legionella quinlivanii, medicine, Clinical Case Report, 030304 developmental biology
الوصف: We describe a strain of Legionella quinlivanii isolated from a bronchoalveolar lavage specimen from an 83-year-old patient in the province of Québec. Identification was done using 16S rRNA sequencing. The strain could replicate efficiently in human THP-1 macrophages and maintained a low level of cytotoxicity. Upon analyzing the whole genome sequencing data, the icm/dot secretion system was present, but the strain lacked some effector genes known to express proteins toxic to cells. The pathogenicity of this Legionella species should be investigated further.
اللغة: English
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21fab29e4a779b021a4b2a2f3faab9b3
https://europepmc.org/articles/PMC9602882/
Rights: OPEN
رقم الانضمام: edsair.doi.dedup.....21fab29e4a779b021a4b2a2f3faab9b3
قاعدة البيانات: OpenAIRE