The influence of smoking on vitamin D status and calcium metabolism
| العنوان: | The influence of smoking on vitamin D status and calcium metabolism |
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| المؤلفون: | Niklas Rye Jørgensen, C. Brot, Ole Helmer Sørensen |
| المصدر: | European Journal of Clinical Nutrition. 53:920-926 |
| بيانات النشر: | Springer Science and Business Media LLC, 1999. |
| سنة النشر: | 1999 |
| مصطلحات موضوعية: | Vitamin, medicine.medical_specialty, Bone density, Osteocalcin, Osteoporosis, Medicine (miscellaneous), Parathyroid hormone, Biology, Bone and Bones, Phosphates, Bone remodeling, chemistry.chemical_compound, visual_art.visual_artist, Sunbathing, Bone Density, Internal medicine, medicine, Vitamin D and neurology, Humans, Amino Acids, Vitamin D, Calcium metabolism, Nutrition and Dietetics, Smoking, Middle Aged, medicine.disease, Cross-Sectional Studies, Endocrinology, chemistry, Parathyroid Hormone, visual_art, Calcium, Female |
| الوصف: | Objective: To assess the influence of smoking on serum parathyroid hormone (PTH), serum vitamin D metabolites, serum ionized calcium, serum phosphate, and biochemical markers of bone turnover in a cohort of 510 healthy Danish perimenopausal women. Design: A cross-sectional study. Setting: Copenhagen, Denmark. Subjects: Five-hundred-and-ten healthy women aged 45–58 y, included 3–24 months after last menstrual bleeding. None were using hormone replacement therapy. Methods: The women were grouped according to their current smoking status. The two groups were compared with regard to serum levels of 25-hydroxyvitamin D (25OHD) and 1,25-dihydroxyvitamin D (1,25-(OH)2D), intact PTH, ionized calcium and phosphate, osteocalcin, as well as urine pyridinolines. Bone mineral density (BMD) was measured with DEXA-scans. Multiple regression analyses were performed to detect the effect of potentially confounding lifestyle factors, such as calcium and vitamin D intakes, alcohol and coffee consumption, sunbathing, and physical exercise. Results: Fifty percent were current smokers. Smokers had significantly reduced levels of serum 25OHD (P=0.02), 1,25(OH)2D (P=0.001), and PTH (P |
| تدمد: | 1476-5640 0954-3007 |
| DOI: | 10.1038/sj.ejcn.1600870 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217562948fd529216275c27590e258eb https://doi.org/10.1038/sj.ejcn.1600870 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....217562948fd529216275c27590e258eb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14765640 09543007 |
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| DOI: | 10.1038/sj.ejcn.1600870 |