zeta-COP, a subunit of coatomer, is required for COP-coated vesicle assembly
| العنوان: | zeta-COP, a subunit of coatomer, is required for COP-coated vesicle assembly |
|---|---|
| المؤلفون: | L Orci, Gary Tanigawa, Mylène Amherdt, Sayuri Hara-Kuge, James E. Rothman, Felix T. Wieland, Osamu Kuge, M Ravazzola |
| المصدر: | The Journal of Cell Biology |
| بيانات النشر: | Rockefeller University Press, 1993. |
| سنة النشر: | 1993 |
| مصطلحات موضوعية: | DNA, Complementary, Macromolecular Substances, Protein subunit, Molecular Sequence Data, Restriction Mapping, Golgi Apparatus, Coated vesicle, CHO Cells, Biology, Polymerase Chain Reaction, Clathrin, symbols.namesake, Cytosol, GTP-Binding Proteins, Cricetinae, RhoB GTP-Binding Protein, Animals, Amino Acid Sequence, rhoB GTP-Binding Protein, DNA Primers, Base Sequence, Vesicle, Brain, Membrane Proteins, Articles, Intracellular Membranes, Cell Biology, Oligonucleotides, Antisense, COP-Coated Vesicles, Golgi apparatus, humanities, Molecular Weight, Liver, Biochemistry, Guanosine 5'-O-(3-Thiotriphosphate), Coatomer, Chromatography, Gel, biology.protein, symbols, Biophysics, Cattle, Carrier Proteins |
| الوصف: | cDNA encoding the 20-kD subunit of coatomer, zeta-COP, predicts a protein of 177-amino acid residues, similar in sequence to AP17 and AP19, subunits of the clathrin adaptor complexes. Polyclonal antibody directed to zeta-COP blocks the binding of coatomer to Golgi membranes and prevents the assembly of COP-coated vesicles on Golgi cisternae. Unlike other coatomer subunits (beta-, beta'-, gamma-, and epsilon-COP), zeta-COP exists in both coatomer bound and free pools. |
| تدمد: | 1540-8140 0021-9525 |
| DOI: | 10.1083/jcb.123.6.1727 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ade07caee7a4fe5f5a3001e37bfc10 https://doi.org/10.1083/jcb.123.6.1727 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....20ade07caee7a4fe5f5a3001e37bfc10 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15408140 00219525 |
|---|---|
| DOI: | 10.1083/jcb.123.6.1727 |