Sensitivity of susceptibility-weighted imaging in detecting developmental venous anomalies and associated cavernomas and microhemorrhages in children
| العنوان: | Sensitivity of susceptibility-weighted imaging in detecting developmental venous anomalies and associated cavernomas and microhemorrhages in children |
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| المؤلفون: | Andrea Poretti, Allen Young, Reema Goel, Thierry A.G.M. Huisman, Thangamadhan Bosemani |
| المصدر: | Neuroradiology. 59:797-802 |
| بيانات النشر: | Springer Science and Business Media LLC, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Neurology, Adolescent, Contrast Media, Sensitivity and Specificity, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Neuroimaging, medicine, Humans, Radiology, Nuclear Medicine and imaging, Child, Cerebral Hemorrhage, Neuroradiology, Central Nervous System Vascular Malformations, medicine.diagnostic_test, business.industry, Infant, Magnetic resonance imaging, Gold standard (test), Cavernous malformations, medicine.disease, Hemangioma, Cavernous, Child, Preschool, Susceptibility weighted imaging, Female, Neurology (clinical), Radiology, Neurosurgery, Cardiology and Cardiovascular Medicine, business, Magnetic Resonance Angiography, 030217 neurology & neurosurgery |
| الوصف: | Developmental venous anomalies (DVA) are common neuroimaging abnormalities that are traditionally diagnosed by contrast-enhanced T1-weighted images as the gold standard. We aimed to evaluate the sensitivity of SWI in detecting DVA and associated cavernous malformations (CM) and microhemorrhages in children in order to determine if SWI may replace contrast-enhanced MRI sequences. Contrast-enhanced T1-weighted images were used as diagnostic gold standard for DVA. The presence of DVA was qualitatively assessed on axial SWI and T2-weighted images by an experienced pediatric neuroradiologist. In addition, the presence of CM and microhemorrhages was evaluated on SWI and contrast-enhanced T1-weighted images. Fifty-seven children with DVA (34 males, mean age at neuroimaging 11.2 years, range 1 month to 17.9 years) were included in this study. Forty-nine out of 57 DVA were identified on SWI (sensitivity of 86%) and 16 out of 57 DVA were detected on T2-weighted images (sensitivity of 28.1%). General anesthesia-related changes in brain hemodynamics and oxygenation were most likely responsible for the majority of SWI false negative. CM were detected in 12 patients on axial SWI, but only in six on contrast-enhanced T1-weighted images. Associated microhemorrhages could be identified in four patients on both axial SWI and contrast-enhanced T1-weighted images, although more numerous and conspicuous on SWI. SWI can identify DVA and associated cavernous malformations and microhemorrhages with high sensitivity, obviating the need for contrast-enhanced MRI sequences. |
| تدمد: | 1432-1920 0028-3940 |
| DOI: | 10.1007/s00234-017-1867-2 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a23d14ff63944734eba5a7c73fd70e https://doi.org/10.1007/s00234-017-1867-2 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....20a23d14ff63944734eba5a7c73fd70e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14321920 00283940 |
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| DOI: | 10.1007/s00234-017-1867-2 |