Hyperintense Basilar Artery on FLAIR MR Imaging: Diagnostic Accuracy and Clinical Impact in Patients with Acute Brain Stem Stroke
| العنوان: | Hyperintense Basilar Artery on FLAIR MR Imaging: Diagnostic Accuracy and Clinical Impact in Patients with Acute Brain Stem Stroke |
|---|---|
| المؤلفون: | Donald Lobsien, Peter Voigt, Matthias Gawlitza, J Otto, K-T Hoffmann, Ulf Quäschling, Carsten Hobohm |
| المصدر: | AJNR Am J Neuroradiol |
| بيانات النشر: | American Society of Neuroradiology (ASNR), 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Lumen (anatomy), Arterial Occlusive Diseases, Diagnostic accuracy, Fluid-attenuated inversion recovery, Sensitivity and Specificity, Brain stem stroke, medicine.artery, medicine, Basilar artery, Humans, Radiology, Nuclear Medicine and imaging, In patient, Aged, Retrospective Studies, Aged, 80 and over, Foramen magnum, business.industry, Brain, Middle Aged, Magnetic Resonance Imaging, Mr imaging, Stroke, medicine.anatomical_structure, Basilar Artery, cardiovascular system, Female, sense organs, Neurology (clinical), Radiology, business, Brain Stem |
| الوصف: | BACKGROUND AND PURPOSE: FLAIR-hyperintense vessels are known to be a sign of sluggish collateral blood flow in hemispheric vessel occlusion. Additionally, they seem to have a prognostic implication. The aim of the current study was to evaluate the hyperintense configuration of the basilar artery (FLAIR-hyperintense basilar artery) as a marker of basilar artery occlusion and as a predictor of patient outcome. MATERIALS AND METHODS: We retrospectively identified 20 patients with basilar artery occlusion who initially underwent MR imaging with subsequent DSA. The diagnostic accuracy of the FLAIR-hyperintense basilar artery sign was tested by 4 independent readers in a case-control design, and the relation among FLAIR-hyperintense basilar artery and DWI posterior circulation–ASPECTS, patient outcome, and patient survival was evaluated. To grade the extent of the FLAIR-hyperintense basilar artery sign, we generated a score by counting the number of sections from the basilar tip to the foramen magnum in which a hyperintense signal in the vessel lumen was present multiplied by the section thickness. RESULTS: The FLAIR-hyperintense basilar artery sign showed moderate sensitivity (65%–95%) but very good specificity (95%–100%) and accuracy (85%–93%) for the detection of basilar artery occlusion. Substantial or excellent inter-reader agreement was observed (Cohen κ, 0.64–0.85). The FLAIR-hyperintense basilar artery inversely correlated with the posterior circulation–ASPECTS (r = −0.67, P = .01). Higher FLAIR-hyperintense basilar artery scores were associated with patient death (28.3 ± 13.7 versus 13.4 ± 11.1, P < .05). CONCLUSIONS: The FLAIR-hyperintense basilar artery sign proved to be a valuable marker of vessel occlusion and may substantially support the diagnosis of basilar artery occlusion. The established FLAIR-hyperintense basilar artery score may be helpful for the prediction of individual patient survival. |
| تدمد: | 1936-959X 0195-6108 |
| DOI: | 10.3174/ajnr.a3961 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2058452e4aa603f59974e3046e1ebe5c https://doi.org/10.3174/ajnr.a3961 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....2058452e4aa603f59974e3046e1ebe5c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1936959X 01956108 |
|---|---|
| DOI: | 10.3174/ajnr.a3961 |