A novel approach for in-office tooth bleaching with 6% H2O2/TiO_N and LED/laser system-a controlled, triple-blinded, randomized clinical trial
| العنوان: | A novel approach for in-office tooth bleaching with 6% H2O2/TiO_N and LED/laser system-a controlled, triple-blinded, randomized clinical trial |
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| المؤلفون: | Priscila Sadalla Ismael Bernardi, Tamara Carolina Trevisan, Eduardo Fernández, Janaína Freitas Bortolatto, Lívia Nordi Dovigo, Osmir Batista de Oliveira Júnior, Hermes Pretel, Alessandro Dourado Loguercio |
| المساهمون: | Universidade Estadual Paulista (Unesp), Universidad de Chile, Universidade Estadual de Ponta Grossa (UEPG) |
| المصدر: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Post hoc, Dentistry, Dermatology, System a, law.invention, 03 medical and health sciences, chemistry.chemical_compound, Young Adult, 0302 clinical medicine, Randomized controlled trial, law, medicine, Nanotechnology, Humans, 030212 general & internal medicine, Hydrogen peroxide, Tooth Bleaching Agents, Tooth sensitivity, business.industry, Repeated measures design, 030206 dentistry, Hydrogen Peroxide, Dentin Sensitivity, Surgery, Clinical trial, Treatment Outcome, chemistry, Tooth Sensitivity, Titanium dioxide, Tooth bleaching, Female, Analysis of variance, Lasers, Semiconductor, business |
| الوصف: | Made available in DSpace on 2018-12-11T16:41:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-04-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) The purpose of this randomized, parallel, triple-blinded clinical trial was to compare efficacy and tooth sensitivity (TS) after use of an in-office bleaching agent of 6 % hydrogen peroxide containing nanoparticles of nitrogen-doped titanium oxide (HP6) vs. 35 % hydrogen peroxide (HP35). Forty-eight volunteers were randomly divided either a HP6 or HP35. Two clinical sessions were performed with an interval of 7 days between them for each group. In each session, two consecutive applications of each bleaching agent were performed and activated by a hybrid LED/laser light. Efficacy was determined by color alteration (ΔE), recorded with reflectance spectroscopy. It was assessed at baseline and after the first and second bleaching session. TS was characterized according to occurrence, intensity, duration, and type. Efficacy was analyzed by repeated measures analysis of variance (ANOVA) and post hoc Bonferroni test, and TS was analyzed by means of chi2 test (α = 0.05). For HP35, highest and significant values of ΔE were found after bleaching when compared to HP6 (p = 0.002). However, HP35 showed a significantly higher occurrence of TS than HP6 (p = 0.008). Also, intensity and duration were higher in HP35. The majority of volunteers classified the type experienced in their sensitivity in the form of a “shock.” The use of HP6 despite reducing efficacy when compared to an in-office bleaching in higher concentration (35 %) produced less tooth sensitivity. Clinical relevance: In terms of tooth sensitivity, the use of lower concentrations of in-office bleaching should be the first choice, suggesting greater biocompatibility and safety compared to a conventional HP35. Department of Restorative Dentistry School of Dentistry UNESP - Universidade Estadual Paulista, 1680 Humaitá Street Department of Restorative Dentistry School of Dentistry School of Dentistry of Santiago Universidad de Chile, Sergio Livingston 943, Independencia Department of Restorative Dentistry School of Dentistry Faculdade de Odontologia Universidade Estadual de Ponta Grossa, Rua Carlos Cavalcanti, 4748 Department of Restorative Dentistry School of Dentistry UNESP - Universidade Estadual Paulista, 1680 Humaitá Street |
| تدمد: | 1435-604X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa26da0309e98242fd08ec3e8de19d9 https://pubmed.ncbi.nlm.nih.gov/26796706 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....1fa26da0309e98242fd08ec3e8de19d9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1435604X |
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