Emergence of human G9 rotavirus with an exceptionally high frequency in children admitted to hospital with diarrhea in Chiang Mai, Thailand
| العنوان: | Emergence of human G9 rotavirus with an exceptionally high frequency in children admitted to hospital with diarrhea in Chiang Mai, Thailand |
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| المؤلفون: | Supin Tonusin, Varunee Maneerat, Supatra Peerakome, Niwat Maneekarn, Penpuck Sornchai, Hiroshi Ushijima, Lumduan Wongsawasdi, Fumihiro Yagyu, Shoko Okitsu, Pattara Khamrin, Chantana Khamwan |
| المصدر: | Journal of Medical Virology. 78:273-280 |
| بيانات النشر: | Wiley, 2005. |
| سنة النشر: | 2005 |
| مصطلحات موضوعية: | Rotavirus, Genes, Viral, Molecular Sequence Data, Biology, medicine.disease_cause, Group A, Rotavirus Infections, Group B, Feces, Species Specificity, Sequence Homology, Nucleic Acid, Virology, parasitic diseases, Genotype, medicine, Humans, Antigens, Viral, Strain (biology), Infant, Newborn, Nucleic acid sequence, Infant, Thailand, Hospitals, Diarrhea, Infectious Diseases, Child, Preschool, Capsid Proteins, medicine.symptom |
| الوصف: | Among 315 fecal specimens collected from children hospitalized with diarrhea in Chiang Mai, Thailand, in 2000-2001, group A rotavirus was detected in 107 (34.0%). Of these, 98 (91.6%) were G9, 6 (5.6%) were G3 and 3 (2.8%) were G2, respectively. Identification of their P-types demonstrated that 103 (96.3%) were P[8], 3 (2.8%) were P[4], and 1 (0.9%) was P[3] genotypes. Determination of G- and P-type combination revealed that all of G9 isolates were associated with P[8]. G9P[8] was the most predominant genotype and accounted for the majority (91.6%) of rotaviruses detected in this study. Molecular characterization of these G9 isolates demonstrated that all had long electropherotype, 96 of 98 (98.0%) belonged to subgroup II, one belonged to subgroup I and the other one was subgroup unidentifiable. All of G9 isolates possessed NSP4 genetic group B except for one isolate that showed dual genetic group specificities, B and C. The full-length VP7 gene nucleotide sequences among 15 representatives of these G9 strains were found to be highly homologous with percent identities of 99.3%-100%. Comparison with other G9 strains recently isolated showed that their nucleotide sequences were closely related to those of the US strain, US1205 (98.7%-99.0%) and Thai strain, 97CM108 (98.1%-99.0%). Interestingly, they were most closely related to the Japanese strain, 00-SG2509VP7, isolated in the same epidemic season, with percent nucleotide sequence identity of 99.4%-99.8%. The data imply that G9 strains isolated in this study and a G9 strain isolated in Japan in the year 2000 might have descended from the same ancestor. |
| تدمد: | 1096-9071 0146-6615 |
| DOI: | 10.1002/jmv.20536 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0f2533bda0b247621b36f2d4c79ed9 https://doi.org/10.1002/jmv.20536 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....1d0f2533bda0b247621b36f2d4c79ed9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10969071 01466615 |
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| DOI: | 10.1002/jmv.20536 |