The assessment of correlation and prognosis among 18F-FDG uptake parameters, Glut1, pStat1 and pStat3 in surgically resected non-small cell lung cancer patients
| العنوان: | The assessment of correlation and prognosis among 18F-FDG uptake parameters, Glut1, pStat1 and pStat3 in surgically resected non-small cell lung cancer patients |
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| المؤلفون: | Shinzo Takamori, Takamichi Murakami, Koichi Azuma, Eiji Sadashima, Hayato Kaida, Masatoshi Ishibashi, Axel Rominger, Jun Akiba, Akihiko Kawahara, Kazunari Ishii, Kiminori Fujimoto, Satoshi Hattori |
| المصدر: | Oncotarget Kaida, Hayato; Azuma, Koichi; Kawahara, Akihiko; Sadashima, Eiji; Hattori, Satoshi; Takamori, Shinzo; Akiba, Jun; Fujimoto, Kiminori; Rominger, Axel; Murakami, Takamichi; Ishii, Kazunari; Ishibashi, Masatoshi (2018). The assessment of correlation and prognosis among 18F-FDG uptake parameters, Glut1, pStat1 and pStat3 in surgically resected non-small cell lung cancer patients. OncoTarget, 9(62), pp. 31971-31984. Impact Journals LLC 10.18632/oncotarget.25865 <http://dx.doi.org/10.18632/oncotarget.25865> |
| بيانات النشر: | Impact Journals LLC, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Oncology, medicine.medical_specialty, University faculty, 610 Medicine & health, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Lung cancer, non-small cell lung cancer, volumetric parameters, business.industry, Fdg uptake, pStat3, Nsclc cell, pStat1, University hospital, medicine.disease, Tumor tissue, Glut1, carbohydrates (lipids), 030220 oncology & carcinogenesis, Non small cell, business, Research Paper |
| الوصف: | // Hayato Kaida 1 , Koichi Azuma 2 , Akihiko Kawahara 3 , Eiji Sadashima 4 , Satoshi Hattori 5 , Shinzo Takamori 6 , Jun Akiba 3 , Kiminori Fujimoto 7 , Axel Rominger 8 , Takamichi Murakami 9 , Kazunari Ishii 1 and Masatoshi Ishibashi 10 1 Department of Radiology, Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan 2 Division of Respirology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan 3 Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Fukuoka, Japan 4 Life Science, Saga-Ken Medical Centre Koseikan, Saga, Saga, Japan 5 Department of Biomedical Statistics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan 6 Department of Surgery, Kurume University School of Medicine, Kurume, Fukuoka, Japan 7 Department of Radiology, Kurume University School of Medicine, Kurume, Fukuoka, Japan 8 Department of Nuclear Medicine, Inselspital, Bern University Hospital, Bern, Switzerland 9 Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan 10 Department of Radiology, Fukuoka Tokushukai Medical Center, Kasuga, Fukuoka, Japan Correspondence to: Hayato Kaida, email: kaida@med.kindai.ac.jp Keywords: non-small cell lung cancer; volumetric parameters; Glut1; pStat1; pStat3 Received: June 09, 2018 Accepted: July 13, 2018 Published: August 10, 2018 ABSTRACT Introduction: To assess the correlation among 18 F-FDG uptake, Glut1, pStat1 and pStat3, and to investigate the relationship between the prognosis and 18 F-FDG uptake and these molecular markers in surgically resected non-small cell lung cancer (NSCLC) patients. Results: Knockdown of Glut1 led to a significant increase in pStat1 expression. Glut1 expression positively correlated with the SUVmax, SUVmean, and TLG significantly ( P |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1949-2553 |
| DOI: | 10.18632/oncotarget.25865 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab4f7eb3942b9082c2917fa0642560e http://europepmc.org/articles/PMC6112832 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....1ab4f7eb3942b9082c2917fa0642560e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19492553 |
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| DOI: | 10.18632/oncotarget.25865 |