Evaluating the role of local host factors in the candidal colonization of oral cavity: A review update
| العنوان: | Evaluating the role of local host factors in the candidal colonization of oral cavity: A review update |
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| المؤلفون: | Meher Rizvi, Uqba Raza, Imran Khan, Nikhat Manzoor, Tanveer Ahmad, Shubhangi Premchandani |
| المصدر: | National Journal of Maxillofacial Surgery |
| بيانات النشر: | Wolters Kluwer - Medknow, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Saliva, medicine.medical_treatment, candidal carriage, Dentistry, Review Article, Oral cavity, 03 medical and health sciences, 0302 clinical medicine, Candida albicans, medicine, Colonization, Palatal obturator, Craniofacial, 030223 otorhinolaryngology, biology, business.industry, 030206 dentistry, biology.organism_classification, Review article, stomatognathic diseases, orofacial clefts, Surgery, Oral Surgery, Dentures, business, cleft lip and palate |
| الوصف: | Human oral cavity is home to a number of organisms, Candida albicans being one of them. This review article aims at understanding the correlation between the oral candidal colonization and the local host factors that may influence it with special emphasis on congenital craniofacial anomalies such as cleft lip and palate (CLP). Various scientific databases were searched online and relevant articles were selected based on the inclusion criteria. A comparative study was done to understand the interdependence of various factors (including CLP) and oral candidal colonization. The results revealed a strong association of certain local host factors which may influence the oral colonization of Candida species. Factors such as mucosal barrier, salivary constituents and quantity of saliva, congenital deformities like CLP, oral prostheses such as dentures/palatal obturators and fixed orthodontic appliances (FOAs) were identified. All these factors may directly affect the growth of Candida in the oral cavity. Although numerous studies have pointed a positive correlation between Oral Candidal colonization and local host factors such as oral prostheses, FOA, and oral mucosal barrier only one study has been done, in the Indian subcontinent with respect to the correlation of candidal colonization and CLP. After the evaluation of all the factors mentioned in various case studies, it can be concluded that the presence of local host factors such as orofacial clefts, dental prostheses, FOA, xerostomia, and atrophy of the oral mucous membrane lead to significant increase in candidal colonization, but since very few studies in regard to CLP have been done worldwide and in India, in particular, further studies are warranted. |
| اللغة: | English |
| تدمد: | 2229-3418 0975-5950 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c25786c9fc3a647749b217484fa94c http://europepmc.org/articles/PMC8051668 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....19c25786c9fc3a647749b217484fa94c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22293418 09755950 |
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