Blood Pressure Profiles 5 to 10 Years After Transplant in Pediatric Solid Organ Recipients

التفاصيل البيبلوغرافية
العنوان: Blood Pressure Profiles 5 to 10 Years After Transplant in Pediatric Solid Organ Recipients
المؤلفون: Mikko P. Pakarinen, Timo Jahnukainen, Erik Qvist, Hannu Jalanko, Juuso Tainio, Jenni Miettinen, Tuula Hölttä
المصدر: J Clin Hypertens (Greenwich)
بيانات النشر: John Wiley and Sons Inc., 2015.
سنة النشر: 2015
مصطلحات موضوعية: Male, medicine.medical_specialty, Ambulatory blood pressure, Adolescent, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Renal function, Blood Pressure, Liver transplantation, Risk Factors, Internal medicine, Internal Medicine, medicine, Humans, Obesity, Risk factor, Child, Kidney transplantation, Dyslipidemias, Retrospective Studies, Heart transplantation, business.industry, Incidence, Graft Survival, Infant, Blood Pressure Monitoring, Ambulatory, medicine.disease, Original Papers, Kidney Transplantation, Transplant Recipients, Surgery, Circadian Rhythm, Liver Transplantation, Blood pressure, Cross-Sectional Studies, Cardiovascular Diseases, Child, Preschool, Ambulatory, Hypertension, Cardiology, Heart Transplantation, Female, Cardiology and Cardiovascular Medicine, business, Follow-Up Studies
الوصف: Arterial hypertension is a major risk factor for cardiovascular disease after solid organ transplantation, emphasizing the need for blood pressure (BP) monitoring. The authors studied 24-hour ambulatory BP monitoring (ABPM) parameters (index, load, dipping) and their predictive value with regard to hypertension as well as correlations with graft function and metabolic parameters such as obesity and dyslipidemias. The ABPM profiles of 111 renal, 29 heart, and 13 liver transplant recipients were retrospectively analyzed 5 to 10 years after transplant (median 5.1 years). The BP profiles among the different transplant groups were similar. The BP index and load were abnormal especially at nighttime and the nocturnal BP dipping was often blunted (in 49% to 83% of the patients). The BP variables were found to be equally valued when assessing hypertension. BP load of 50% instead of 25% seems to be a more adequate cutoff value. The BP variables correlated poorly with the metabolic parameters and kidney function. Antihypertensive medication did not notably change the ABPM profile in renal transplant recipients. Hypertension, including nocturnal hypertension, is present in children receiving solid organ transplant, underlining the importance of use of ABPM in the follow-up of these patients.
اللغة: English
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1928ca22ba008abf8de8cda2eda708ee
https://europepmc.org/articles/PMC8031723/
Rights: OPEN
رقم الانضمام: edsair.doi.dedup.....1928ca22ba008abf8de8cda2eda708ee
قاعدة البيانات: OpenAIRE