Outer membrane vesicles of Porphyromonas gingivalis: Novel communication tool and strategy
| العنوان: | Outer membrane vesicles of Porphyromonas gingivalis: Novel communication tool and strategy |
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| المؤلفون: | Yuhan He, Airi Tanai, Jiajie Guo, Katsuhiko Hirota, Hirohiko Okamura, Kaya Yoshida, Noriko Shiotsu, Yoko Uchida-Fukuhara, Mika Ikegame, Yao Weng |
| المصدر: | The Japanese Dental Science Review Japanese Dental Science Review, Vol 57, Iss, Pp 138-146 (2021) |
| بيانات النشر: | Elsevier, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | biology, Host cell interaction, Microorganism, Vesicle, RK1-715, Outer membrane vesicles, Review Article, Immune modulation, Extracellular vesicles, biology.organism_classification, Cell biology, Dentistry, In vivo imaging, Signal transduction, Bacterial outer membrane, General Dentistry, Porphyromonas gingivalis, Bacteria |
| الوصف: | Extracellular vesicles (EVs) have been recognized as a universal method of cellular communications and are reportedly produced in bacteria, archaea, and eukaryotes. Bacterial EVs are often called “Outer Membrane Vesicles” (OMVs) as they were the result of a controlled blebbing of the outer membrane of gram-negative bacteria such as Porphyromonas gingivalis (P. gingivalis). Bacterial EVs are natural messengers, implicated in intra- and inter-species cell-to-cell communication among microorganism populations present in microbiota. Bacteria can incorporate their pathogens into OMVs; the content of OMVs differs, depending on the type of bacteria. The production of distinct types of OMVs can be mediated by different factors and routes. A recent study highlighted OMVs ability to carry crucial molecules implicated in immune modulation, and, nowadays, they are considered as a way to communicate and transfer messages from the bacteria to the host and vice versa. This review article focuses on the current understanding of OMVs produced from major oral bacteria, P. gingivalis: generation, characteristics, and contents as well as the involvement in signal transduction of host cells and systemic diseases. Our recent study regarding the action of P. gingivalis OMVs in the living body is also summarized. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2213-6851 1882-7616 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fb291b195dc6fa60ef795fbafe4cd4 http://europepmc.org/articles/PMC8399048 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....18fb291b195dc6fa60ef795fbafe4cd4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22136851 18827616 |
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