Novel adenovirus associated with necrotizing bronchiolitis in a captive reindeer ( Rangifer tarandus)
| العنوان: | Novel adenovirus associated with necrotizing bronchiolitis in a captive reindeer ( Rangifer tarandus) |
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| المؤلفون: | Jonathan M. Williams, Márton Z. Vidovszky, Charlotte Plummer, Sonja Jeckel, Julian Chantrey, Hannah Davies, Henny M. Martineau, Akbar Dastjerdi, Balázs Harrach, Camille Longue, Jennifer Irving |
| المصدر: | TRANSBOUNDARY AND EMERGING DISEASES |
| بيانات النشر: | Hindawi Limited, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, Adenoviridae Infections, animal diseases, viruses, Necrotizing bronchiolitis, Cattle Diseases, Aspiration pneumonia, Adenoviridae, Atadenovirus, parasitic diseases, medicine, Animals, Lung, Bovine adenovirus, General Veterinary, General Immunology and Microbiology, biology, Deer, Ruminants, General Medicine, medicine.disease, biology.organism_classification, Virology, Mastadenovirus, Pneumonia, Family Adenoviridae, medicine.anatomical_structure, Bronchiolitis, Cattle, Reindeer |
| الوصف: | Adenoviruses cause a range of major diseases across many diverse animal species including ruminants. They are classified into six genera in the family Adenoviridae. In deer species, two adenoviruses are currently recognized: deer adenovirus 1 in the Atadenovirus genus, and deer adenovirus 2 in the Mastadenovirus genus. Deer adenovirus 1 causes adenovirus haemorrhagic disease with high fatality in black-tailed and mule deer in North America. Conversely, deer adenovirus 2 was incidentally detected from a healthy white-tailed deer fawn, but experimentally it has been shown to cause pyrexia, cough and moderate to severe haemorrhage. Here, we detected a novel adenovirus, reindeer adenovirus 1, from lung lesions of a 5-year-old male reindeer (Rangifer tarandus). This animal presented with aspiration pneumonia and necrotizing bronchiolitis following a period of clinical weakness, nasal discharge and wasting. Histopathological examination of the lung revealed large intranuclear basophilic inclusions associated with the areas of necrotizing bronchiolitis. Next generation sequencing of the lung tissue identified a novel mastadenovirus with close similarity to deer adenovirus 2 and bovine adenovirus 3. To our knowledge, this is the first report of a deer mastadenovirus associated with necrotizing bronchiolitis in captive reindeer. |
| وصف الملف: | application/pdf |
| تدمد: | 1865-1682 1865-1674 |
| DOI: | 10.1111/tbed.14374 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a88c8568b6b930cabb7acde00e07cd https://doi.org/10.1111/tbed.14374 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....14a88c8568b6b930cabb7acde00e07cd |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18651682 18651674 |
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| DOI: | 10.1111/tbed.14374 |