Regulation of growth–defense balance by the JASMONATE ZIM‐DOMAIN (JAZ)‐MYC transcriptional module
| العنوان: | Regulation of growth–defense balance by the JASMONATE ZIM‐DOMAIN (JAZ)‐MYC transcriptional module |
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| المؤلفون: | Koichi Sugimoto, George Kapali, Marcelo Lattarulo Campos, Xiu Fang Xin, Yuki Yoshida, Gregg A. Howe, Sheng Yang He, Ian T. Major, Dalton de Oliveira Ferreira |
| المصدر: | The New Phytologist |
| بيانات النشر: | Wiley, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Chlorophyll, 0106 biological sciences, 0301 basic medicine, Transcription, Genetic, Physiology, Mutant, Arabidopsis, Flowers, Cyclopentanes, Plant Science, plant hormone, Biology, Plant Roots, gene cluster, 01 natural sciences, plant–insect interaction, Anthocyanins, 03 medical and health sciences, Gene Expression Regulation, Plant, plant defense, Pseudomonas syringae, Arabidopsis thaliana, RNA, Messenger, Oxylipins, Jasmonate, Gene, Transcription factor, Psychological repression, Disease Resistance, Genetics, Full Paper, Arabidopsis Proteins, Research, fungi, Epistasis, Genetic, glucosinolate, Full Papers, biology.organism_classification, 3. Good health, Plant Leaves, 030104 developmental biology, Mutation, triterpenoid, Plant hormone, growth–defense tradeoffs, Signal Transduction, Transcription Factors, jasmonate (JA), 010606 plant biology & botany |
| الوصف: | Summary The plant hormone jasmonate (JA) promotes the degradation of JASMONATE ZIM‐DOMAIN (JAZ) proteins to relieve repression on diverse transcription factors (TFs) that execute JA responses. However, little is known about how combinatorial complexity among JAZ–TF interactions maintains control over myriad aspects of growth, development, reproduction, and immunity.We used loss‐of‐function mutations to define epistatic interactions within the core JA signaling pathway and to investigate the contribution of MYC TFs to JA responses in Arabidopsis thaliana.Constitutive JA signaling in a jaz quintuple mutant (jazQ) was largely eliminated by mutations that block JA synthesis or perception. Comparison of jazQ and a jazQ myc2 myc3 myc4 octuple mutant validated known functions of MYC2/3/4 in root growth, chlorophyll degradation, and susceptibility to the pathogen Pseudomonas syringae. We found that MYC TFs also control both the enhanced resistance of jazQ leaves to insect herbivory and restricted leaf growth of jazQ. Epistatic transcriptional profiles mirrored these phenotypes and further showed that triterpenoid biosynthetic and glucosinolate catabolic genes are up‐regulated in jazQ independently of MYC TFs.Our study highlights the utility of genetic epistasis to unravel the complexities of JAZ–TF interactions and demonstrates that MYC TFs exert master control over a JAZ‐repressible transcriptional hierarchy that governs growth–defense balance. See also the Commentary on this article by Wasternack, 215: 1291–1294. |
| تدمد: | 1469-8137 0028-646X |
| DOI: | 10.1111/nph.14638 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1476bb76bb130d8bf4d82e099f96cc30 https://doi.org/10.1111/nph.14638 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....1476bb76bb130d8bf4d82e099f96cc30 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14698137 0028646X |
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| DOI: | 10.1111/nph.14638 |