Sepragel Sinus (Hylan B) as a Postsurgical Dressing for Endoscopic Sinus Surgery
| العنوان: | Sepragel Sinus (Hylan B) as a Postsurgical Dressing for Endoscopic Sinus Surgery |
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| المؤلفون: | David R. Edelstein, Han Jin Cheng, Charles P. Kimmelman |
| المصدر: | Otolaryngology–Head and Neck Surgery. 125:603-608 |
| بيانات النشر: | Wiley, 2001. |
| سنة النشر: | 2001 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Constriction, Pathologic, 03 medical and health sciences, 0302 clinical medicine, Adjuvants, Immunologic, Recurrence, medicine, Humans, Hyaluronic Acid, 030223 otorhinolaryngology, Sinus (anatomy), Pain Measurement, Analysis of Variance, Ethmoid Sinusitis, Pain, Postoperative, Wound Healing, Suppuration, business.industry, Head neck, Outcome measures, Ethmoidectomy, Stent, Endoscopy, Exudates and Transudates, medicine.disease, Bandages, Meatal stenosis, Surgery, Nasal Mucosa, Stenosis, Endoscopic sinus surgery, Treatment Outcome, medicine.anatomical_structure, Otorhinolaryngology, 030220 oncology & carcinogenesis, Chronic Disease, Female, Stents, Nasal Obstruction, business, Gels |
| الوصف: | Objective: To assess the safety and efficacy of Sepragel sinus, a hylan B gel (cross-linked hyaluronic acid molecule), when used as a postoperative dressing after endoscopic sinus surgery as a facilitator of healing and a preventative for scarring and stenosis. Study Design: Ten patients undergoing bilateral endoscopic ethmoidectomy in an outpatient specialty hospital operating room underwent complete filling of a randomly selected right or left ethmoidectomy cavity with Sepragel sinus. Outcome measures were synechiae, middle meatal stenosis, mucosal status, mucosal regeneration, transparency of Sepragel sinus, and subjective pain and congestion. Results: Sepragel sinus significantly improved all outcome measures by week 2 and remained statistically significant for reduction of synechiae and stenosis. Conclusion: Sepragel sinus is useful as a space-occupying gel stent to separate sinus mucosal surfaces. The data strongly support the superiority of Sepragel sinus over no treatment in the control of postethmoidectomy synechiae and middle meatal stenosis, as well as early improvement in mucosal healing and postoperative pain. Significance: Because of its biocompatibility, lack of inflammatory response, transparency, and ability to fill any complex volume, Sepragel sinus offers distinct advantages over currently used stenting materials. (Otolaryngol Head Neck Surg 2001;125:603-8.) |
| تدمد: | 1097-6817 0194-5998 |
| DOI: | 10.1067/mhn.2001.120229 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::143c90499eaf925d4d3cbf5a50458c04 https://doi.org/10.1067/mhn.2001.120229 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....143c90499eaf925d4d3cbf5a50458c04 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10976817 01945998 |
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| DOI: | 10.1067/mhn.2001.120229 |