Auditory cortical contrast enhancing by global winner-take-all inhibitory interactions
| العنوان: | Auditory cortical contrast enhancing by global winner-take-all inhibitory interactions |
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| المؤلفون: | John M. Crook, Henning Scheich, Christoph K. Moeller, Holger Schulze, Eike Budinger, Simone Kurt, Anke Deutscher, Frank W. Ohl |
| المصدر: | PLoS ONE, Vol 3, Iss 3, p e1735 (2008) PLoS ONE |
| بيانات النشر: | Public Library of Science (PLoS), 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | Auditory perception, genetic structures, Computer science, media_common.quotation_subject, lcsh:Medicine, Inhibitory postsynaptic potential, Auditory cortex, Perception, Animals, Contrast (vision), lcsh:Science, media_common, Auditory Cortex, Neuroscience/Cognitive Neuroscience, Multidisciplinary, Mechanism (biology), Neuroscience/Sensory Systems, lcsh:R, Neuroscience/Animal Cognition, Representation (systemics), Receptors, GABA-A, Object (computer science), Winner-take-all, Electrophysiology, Acoustic Stimulation, Auditory Perception, lcsh:Q, Neural Networks, Computer, Gerbillinae, Neuroscience, Algorithms, Research Article |
| الوصف: | Brains decompose the world into discrete objects of perception, thereby facing the problem of how to segregate and selectively address similar objects that are concurrently present in a scene. Theoretical models propose that this could be achieved by neuronal implementations of so-called winner-take-all algorithms where neuronal representations of objects or object features interact in a competitive manner. Here we present evidence for the existence of such a mechanism in an animal species. We present electrophysiological, neuropharmacological and neuroanatomical data which suggest a novel view of the role of GABA(A)-mediated inhibition in primary auditory cortex (AI), where intracortical GABA(A)-mediated inhibition operates on a global scale within a circular map of sound periodicity representation in AI, with functionally inhibitory projections of similar effect from any location throughout the whole map. These interactions could underlie the proposed competitive "winner-take-all" algorithm to support object segregation, e.g., segregation of different speakers in cocktail-party situations. |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137ee32d307f66a8571b1b1bbd30d5e5 http://europepmc.org/articles/PMC2253823?pdf=render |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....137ee32d307f66a8571b1b1bbd30d5e5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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