The kinectome: A comprehensive kinematic map of human motion in health and disease

التفاصيل البيبلوغرافية
العنوان: The kinectome: A comprehensive kinematic map of human motion in health and disease
المؤلفون: Emahnuel Troisi Lopez, Pierpaolo Sorrentino, Marianna Liparoti, Roberta Minino, Arianna Polverino, Antonella Romano, Anna Carotenuto, Enrico Amico, Giuseppe Sorrentino
سنة النشر: 2022
مصطلحات موضوعية: impairment, people, variability, General Neuroscience, Movement, gait analysis, movement pattern, network, Parkinson’s disease, Acceleration, movement pattern, Parkinson Disease, stability, trunk, General Biochemistry, Genetics and Molecular Biology, Biomechanical Phenomena, walking, History and Philosophy of Science, parkinson's disease, gait analysis, network, Parkinson’s disease, Humans, parkinsons-disease, progression, Gait, asymmetry
الوصف: Human voluntary movement stems from the coordinated activations in space and time of many musculoskeletal segments. However, the current methodological approaches to study human movement are still limited to the evaluation of the synergies among a few body elements. Network science can be a useful approach to describe movement as a whole and to extract features that are relevant to understanding both its complex physiology and the pathophysiology of movement disorders. Here, we propose to represent human movement as a network (that we named the kinectome), where nodes represent body points, and edges are defined as the correlations of the accelerations between each pair of them. We applied this framework to healthy individuals and patients with Parkinson's disease, observing that the patients' kinectomes display less symmetrical patterns as compared to healthy controls. Furthermore, we used the kinectomes to successfully identify both healthy and diseased subjects using short gait recordings. Finally, we highlighted topological features that predict the individual clinical impairment in patients. Our results define a novel approach to study human movement. While deceptively simple, this approach is well-grounded, and represents a powerful tool that may be applied to a wide spectrum of frameworks.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124b330296dad689d16c6a8efae5460c
http://hdl.handle.net/11367/108857
Rights: OPEN
رقم الانضمام: edsair.doi.dedup.....124b330296dad689d16c6a8efae5460c
قاعدة البيانات: OpenAIRE