Supplementary Table 1 from Defining Key Signaling Nodes and Therapeutic Biomarkers in NF1-Mutant Cancers
| العنوان: | Supplementary Table 1 from Defining Key Signaling Nodes and Therapeutic Biomarkers in NF1-Mutant Cancers |
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| المؤلفون: | Karen Cichowski, Rachel Ingraham, Thomas DeRaedt, Ophélia Maertens, Jody A. Fromm, Clare F. Malone |
| بيانات النشر: | American Association for Cancer Research (AACR), 2023. |
| سنة النشر: | 2023 |
| الوصف: | PDF file - 75KB, Reported in vitro isoform specificities of PI3K inhibitors. The IC50 (nM) reported in the literature for each PI3K inhibitor against Class IA catalytic isoforms in in vitro binding assays is shown. The source for each data set is listed. A66-(S) is termed a p110alphaspecific inhibitor, AZD-6482 is classified as a p110beta-specific inhibitor, and CAL-101 shows selectivity for p110delta. GDC-0941 does not show significant isoform selectivity. |
| DOI: | 10.1158/2159-8290.22532285.v1 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122105ab0f38d156f0667f45d160d388 https://doi.org/10.1158/2159-8290.22532285.v1 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....122105ab0f38d156f0667f45d160d388 |
| قاعدة البيانات: | OpenAIRE |
| DOI: | 10.1158/2159-8290.22532285.v1 |
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