A DRUG-BASED INTERVENTION STUDY ON THE IMPORTANCE OF BUFFALOES FOR HUMAN SCHISTOSOMA JAPONICUM INFECTION AROUND POYANG LAKE, PEOPLE’S REPUBLIC OF CHINA
| العنوان: | A DRUG-BASED INTERVENTION STUDY ON THE IMPORTANCE OF BUFFALOES FOR HUMAN SCHISTOSOMA JAPONICUM INFECTION AROUND POYANG LAKE, PEOPLE’S REPUBLIC OF CHINA |
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| المؤلفون: | George M. Davis, Guanghan Hu, Gail M. Williams, Donald P. McManus, Adrian Sleigh, Hong-Gen Chen, Darren J. Gray, Jia-Gang Guo, Yuesheng Li, An Ning, Zheng Feng |
| المصدر: | Scopus-Elsevier Europe PubMed Central |
| بيانات النشر: | American Society of Tropical Medicine and Hygiene, 2006. |
| سنة النشر: | 2006 |
| مصطلحات موضوعية: | Veterinary medicine, Disease reservoir, Schistosoma Japonicum Infection, biology, animal diseases, Incidence (epidemiology), Schistosoma japonicum, Zoonosis, Helminthiasis, food and beverages, Schistosomiasis, medicine.disease, biology.organism_classification, Praziquantel, Infectious Diseases, Virology, parasitic diseases, medicine, Parasitology, medicine.drug |
| الوصف: | Schistosomiasis japonica is a zoonosis of major public health importance in southern China. We undertook a drug intervention to test the hypothesis that buffalo are major reservoirs for human infection in the marshlands/lake areas, where one million people are infected. We compared human and buffalo infection rates and intensity in an intervention village (Jishan), where humans and buffalo were treated with praziquantel, and a control village (Hexi), where only humans were treated, in the Poyang Lake region. Over the four-year study, human incidence in Jishan decreased but increased in Hexi. Adjustment of incidence by age, sex, water exposure, year, and village further confirmed the decreased human infection in Jishan. Chemotherapy for buffaloes resulted in a decrease in buffalo infection rates in Jishan, which coincided with the reduction in human infection rates there in the last two years of the study. Mathematical modeling predicted that buffalo are responsible for 75% of human transmission in Jishan. |
| تدمد: | 1476-1645 0002-9637 |
| DOI: | 10.4269/ajtmh.2006.74.335 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1210fff9f5de51188ad87fc45ccfea7c https://doi.org/10.4269/ajtmh.2006.74.335 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....1210fff9f5de51188ad87fc45ccfea7c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14761645 00029637 |
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| DOI: | 10.4269/ajtmh.2006.74.335 |