Multi-strain infections and 'relapse' of Leucocytozoon sabrazesi gametocytes in domestic chickens in southern China
| العنوان: | Multi-strain infections and 'relapse' of Leucocytozoon sabrazesi gametocytes in domestic chickens in southern China |
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| المؤلفون: | Jian Jian Li, Shengfa Liu, Wenting Zhao, Chunhui Qiu, Baowei Cai, Xin-zhuan Su, Wen-feng Peng, Yanwei Qi, Xin-Xin Chen, Mingke Lu, Lingxian Hong |
| المصدر: | PLoS ONE, Vol 9, Iss 4, p e94877 (2014) PLoS ONE |
| بيانات النشر: | Public Library of Science (PLoS), 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Leucocytozoon, China, Hemocytes, Livestock, Plasmodium vivax, Genes, Protozoan, Veterinary Microbiology, lcsh:Medicine, Parasitemia, Research and Analysis Methods, Microbiology, Poultry, Model Organisms, medicine, Gametocyte, Parasite hosting, Animals, Cluster Analysis, lcsh:Science, Protozoan Infections, Animal, Poultry Diseases, Multidisciplinary, biology, Geography, Population Biology, Cytochrome b, lcsh:R, Parasite Physiology, Biology and Life Sciences, Agriculture, Sequence Analysis, DNA, Animal Models, Haemosporida, biology.organism_classification, medicine.disease, Veterinary Parasitology, Virology, Veterinary Diseases, Parasitology, Veterinary Science, lcsh:Q, Seasons, Chickens, Zoology, Malaria, Research Article |
| الوصف: | Leucocytozoon parasites infect many species of avian hosts, including domestic chicken, and can inflict heavy economic loss to the poultry industry. Although the prevalence and distribution of two Leucocytozoon species (L. sabrazesi and L. caulleryi) have been reported in China previously, there are many questions related to the parasite infection that remain unanswered, including population diversity and transmission dynamics in domestic chickens. Here we surveyed chicken blood samples from seven sites in four provinces of China to identify Leucocytozoon infection, characterized parasite diversity within individual infected hosts and between sampling sites, and investigated the dynamics of gametocytemia in chickens over time. We found high infection rates in three of the seven sites. Clustering parasite sequences of the mitochondrial cytochrome oxidase III (coxIII) and cytochrome b (cytb) genes showed lack of grouping according to geographic origins and individual hosts carrying large numbers of L. sabrazesi strains. Monitoring gametocytemia in blood samples from infected chickens over time showed ‘relapse’ or persistence of low-level gametocytemia for 4–5 months, which could be explored as an in vivo model for testing drugs against liver stages of Apicomplexan parasites. This study provides important information on population diversity and transmission dynamics of L. sabrazesi and for disease control. |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102bb671475e3d4413cc8ed3f6293762 http://europepmc.org/articles/PMC3984278?pdf=render |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....102bb671475e3d4413cc8ed3f6293762 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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