A randomized, placebo-controlled, cross-over study of ginger extracts and Ibuprofen in osteoarthritis

التفاصيل البيبلوغرافية
العنوان: A randomized, placebo-controlled, cross-over study of ginger extracts and Ibuprofen in osteoarthritis
المؤلفون: J Barslev, M.S Weidner, K A Christensen, H.-H Ibfelt, L A Andersen, O N Jensen, P Schlichting, Henning Bliddal, A Rosetzsky
المصدر: Osteoarthritis and Cartilage. 8(1):9-12
بيانات النشر: Elsevier BV, 2000.
سنة النشر: 2000
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Visual analogue scale, Ginger Extract, Biomedical Engineering, Ginger, Extracts, Osteoarthritis, Pain, Ibuprofen, Ibuprofen, Osteoarthritis, Ginger, Placebo, law.invention, Double-Blind Method, Randomized controlled trial, Rheumatology, law, Internal medicine, medicine, Humans, Orthopedics and Sports Medicine, Adverse effect, Aged, Aged, 80 and over, Cross-Over Studies, Plants, Medicinal, Plant Extracts, business.industry, Anti-Inflammatory Agents, Non-Steroidal, Middle Aged, medicine.disease, Crossover study, Treatment Outcome, Physical therapy, Patient Compliance, Female, business, Phytotherapy, medicine.drug
الوصف: Summary Objective: Alternative medicine is used extensively by patients with chronic pain due to e.g., osteoarthritis. Only few of these drugs have be tested in a controlled setting and the present study was undertaken to examine the effect of ginger extract, one of the most popular herbal medications. Design: Ginger extract was compared to placebo and Ibuprofen in patients with osteoarthritis of the hip or knee in a controlled, double blind, double dummy, cross-over study with a wash-out period of one week followed by three treatment periods in a randomized sequence, each of three weeks duration. Acetaminophen was used as rescue medication throughout the study. The study was conducted in accordance with Good Clinical Practice (European Guideline for GCP). Results: A ranking of efficacy of the three treatment periods: Ibuprofen>ginger extract>placebo was found for visual analogue scale of pain (Friedman test: 24.65, P
تدمد: 1063-4584
DOI: 10.1053/joca.1999.0264
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff4ab93dee3fd17eec72e5992b23b68
Rights: OPEN
رقم الانضمام: edsair.doi.dedup.....0ff4ab93dee3fd17eec72e5992b23b68
قاعدة البيانات: OpenAIRE
الوصف
تدمد:10634584
DOI:10.1053/joca.1999.0264