التفاصيل البيبلوغرافية
العنوان:
Inhibition of transforming growth factor-beta 2 expression with phosphorothioate antisense oligonucleotides in U937 cells
المؤلفون:
Young Sup Lee , Zhong Jian Shen , Byung Jo Moon , Sang Kook Kim , Jong Won Lee
المصدر:
Bioorganicmedicinal chemistry letters . 9(1)
سنة النشر:
1999
مصطلحات موضوعية:
Clinical Biochemistry , Blotting, Western , Drug Evaluation, Preclinical , Pharmaceutical Science , Codon, Initiator , Antineoplastic Agents , Biochemistry , Transforming Growth Factor beta , Drug Discovery , Gene expression , Humans , Cation Exchange Resins , RNA, Messenger , Molecular Biology , Drug Carriers , U937 cell , Dose-Response Relationship, Drug , Histiocytic lymphoma , Oligonucleotide , Chemistry , Organic Chemistry , U937 Cells , Oligonucleotides, Antisense , Phosphorus Compounds , Thionucleotides , Molecular biology , Lipids , In vitro , Cell culture , Antisense oligonucleotides , Molecular Medicine , Indicators and Reagents , Oxidation-Reduction , Cell Division , Fluorescein-5-isothiocyanate , Transforming growth factor
الوصف:
Four types of phosphorothioate antisense oligonucleotides for transforming growth factor-beta 2 were synthesized and tested for their antisense activity in U937 cells. The full-length phosphorothioate modified antisense analogues exhibited the highest inhibitory effects on the transforming growth factor-beta 2 expression in U937 cells.
تدمد:
0960-894X
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fdec79e979ffc7231c7b8279ad899ac https://pubmed.ncbi.nlm.nih.gov/9990448
Rights:
CLOSED
رقم الانضمام:
edsair.doi.dedup.....0fdec79e979ffc7231c7b8279ad899ac
قاعدة البيانات:
OpenAIRE