Oxygenator thrombosis: an international phenomenon
| العنوان: | Oxygenator thrombosis: an international phenomenon |
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| المؤلفون: | Jennifer Schaadt |
| المصدر: | Perfusion. 14:425-435 |
| بيانات النشر: | SAGE Publications, 1999. |
| سنة النشر: | 1999 |
| مصطلحات موضوعية: | medicine.medical_specialty, Oxygenators, 030204 cardiovascular system & hematology, Fibrin, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, Internal medicine, medicine, Cardiopulmonary bypass, Humans, Radiology, Nuclear Medicine and imaging, Thrombus, Oxygenator, Advanced and Specialized Nursing, Cardiopulmonary Bypass, Hematology, biology, business.industry, Thrombosis, General Medicine, Heparin, medicine.disease, Shunting, 030228 respiratory system, biology.protein, Cardiology, Cardiology and Cardiovascular Medicine, business, Safety Research, medicine.drug |
| الوصف: | Oxygenator thrombosis, despite adequate anticoagulation, has become a recent concern amongst perfusionists worldwide. The phenomenon is characterized by a transient increase in oxygenator inlet pressure of up to 900 mmHg about 10-15 min after the institution of cardiopulmonary bypass (CPB). Depending on the size and location of the thrombus, shunting may occur that compromises gas transfer to the extent where oxygenator change-out is necessary. This article presents various case reports and publications, both domestic and international, detailing this phenomenon. Research hypothesizes that it is the activation of platelets that subsequently may cause the deposition of fibrin, yielding thrombus formation; however, the primary etiology of this phenomenon remains unknown. Possible catalysts include bypass techniques, equipment selection, pharmacological agents, prime and the patient. This paper will review all of the above with an emphasis on the often overlooked factor - the patient, as there are certain variables in patient hematology that provoke a hypercoagulable state leading to thrombosis, including blood type, genetics, age, disease state, gender and heparin. |
| تدمد: | 1477-111X 0267-6591 |
| DOI: | 10.1177/026765919901400605 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8ec34fead1acf1cdd3c67a4f602952 https://doi.org/10.1177/026765919901400605 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....0d8ec34fead1acf1cdd3c67a4f602952 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1477111X 02676591 |
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| DOI: | 10.1177/026765919901400605 |