Relationships between neuropsychological impairments and functional outcome eight years after severe traumatic brain injury: Results from the PariS-TBI study
| العنوان: | Relationships between neuropsychological impairments and functional outcome eight years after severe traumatic brain injury: Results from the PariS-TBI study |
|---|---|
| المؤلفون: | P. Azouvi, Pascale Pradat-Diehl, Alexis Ruet, Marie Swaenepoël, Philippe Aegerter, Claire Jourdan, Layide Meaude, Gaëlle Nelson, Eleonore Bayen, Idir Ghout, Claire Vallat-Azouvi, James Charanton |
| المساهمون: | Fonctionnement et Dysfonctionnement Cognitifs : Les âges de la vie (DysCo), Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN), Centre Universitaire des Maladies Rénales [CHU Caen] (CUMR Caen), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), GRC 24 : Handicap Moteur et Cognitif et Réadaptation (HaMCRe ), Sorbonne Université (SU), Hôpital Ambroise Paré [AP-HP], Laboratoire d'Imagerie Biomédicale (LIB), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), GIRCI-IF - Cellule Méthodologie – Fondation A. de Rothschild, Vieillissement et Maladies chroniques : approches épidémiologique et de santé publique (VIMA), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Ressources francilien du traumatisme crânien [Paris], Hôpital Lapeyronie [Montpellier] (CHU), Hôpital Raymond Poincaré [AP-HP], AP-HP. Université Paris Saclay, Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay |
| المصدر: | Brain Injury Brain Injury, 2021, 35 (9), pp.1001-1010. ⟨10.1080/02699052.2021.1933180⟩ |
| بيانات النشر: | HAL CCSD, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Longitudinal study, [SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior, Traumatic brain injury, business.industry, Neuroscience (miscellaneous), Neuropsychology, Glasgow Outcome Scale, Life satisfaction, [SHS.PSY]Humanities and Social Sciences/Psychology, Cognition, macromolecular substances, Neuropsychological Tests, medicine.disease, Outcome (game theory), Brain Injuries, Brain Injuries, Traumatic, [SCCO.PSYC]Cognitive science/Psychology, Developmental and Educational Psychology, medicine, Humans, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Longitudinal Studies, Neurology (clinical), business, Clinical psychology |
| الوصف: | The objective was to assess the relationships between neuropsychological impairments, functional outcome and life satisfaction in a longitudinal study of patients after a severe traumatic brain injury (TBI) (PariS-TBI study).Out of 243 survivors, 86 were evaluated 8 years post-injury. They did not significantly differ from patients lost-to-follow up except for the latter being more frequently students or unemployed before the injury.Outcome measures included the Glasgow Outcome Scale-Extended (GOS-E), a functional independence questionnaire, employment, mood, fatigue and satisfaction with life. Neuropsychological outcome was assessed by two ways: performance-based outcome measures, using neuropsychological tests and patient and relative-based measures.Neuropsychological measures were not significantly related to initial injury severity nor to gender, but were significantly related to age and education. After statistical correction for multiple comparisons, cognitive testing and cognitive questionnaires were significantly correlated with most outcome measures. By contrast, satisfaction with life was only related with patient-rated questionnaires. A regression analysis showed that the Trail-Making-Test-A was the best predictor of functional outcome, in addition to education duration.Cognitive measures, particularly slowed information processing speed, were significant indicators of functional outcome at a long-term post-injury, beyond and above demographics or injury severity measures. |
| اللغة: | English |
| تدمد: | 0269-9052 1362-301X |
| DOI: | 10.1080/02699052.2021.1933180⟩ |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bce1a63eb614a1f2131e953f26a02b8 https://hal-univ-paris8.archives-ouvertes.fr/hal-03814334 |
| رقم الانضمام: | edsair.doi.dedup.....0bce1a63eb614a1f2131e953f26a02b8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 02699052 1362301X |
|---|---|
| DOI: | 10.1080/02699052.2021.1933180⟩ |